PROMISE Registry: PROspective Study on Management of Ischemic Stroke Secondary to mEvo Registry
Indiana University
Summary
Investigators are conducting a real world, observational, prospective, multicenter study to better understand treatment for patients with MeVo and distal vessel occlusions in the U.S post publication of recent MeVO trials.
Description
The primary objective of this study is to better understand the change in landscape, post clinical trials publication, of the management of medium vessel occlusion (MeVO) causing acute ischemic strokes (AIS) in the first 24 hours. This study will help us better understand the "equipoise" in the eyes of practicing physicians across the U.S. Investigators will include patients with MevO treated with mechanical thrombectomy as well as patients treated medically. Study design: This prospective, multicenter, observational study will include patients treated with best medical treatment (BMT) and pa…
Eligibility
- Age range
- 18–85 years
- Sex
- All
- Healthy volunteers
- No
Inclusion 1. Acute ischemic stroke clinically eligible for immediate EVT 2. Age ≥18 - 85 years of age 3. Time from onset (or last-seen-well) to 24 hours 4. Disabling stroke defined as follows: A. Baseline National Institutes of Health Stroke Scale (NIHSS) score \>5 B. Baseline NIHSS 3-5 with disabling deficit (e.g., hemianopia, aphasia, loss of hand function) as determined and agreed upon by two physicians in context of the patient's life 5. Confirmed treatable MeVO based on neurovascular non-invasive imaging (CTA or MRA), at one or more of the following locations: M2 or M3 segment, A2 or…
Location
- IU Health Neuroscience CenterIndianapolis, Indiana