Sukirth M Ganesan, BDS, PhD
This study aims to see how a toothpaste with arginine affects bacteria below the gum line compared to a regular fluoride toothpaste. It focuses on people with gum disease who are already getting ongoing dental care. The main questions it aims to answer are: * How does an arginine toothpaste affect the bacteria below the gumline? * How does a fluoride toothpaste affect the bacteria below the gumline? Participants will: * Use fluoride toothpaste or arginine toothpaste twice daily for 6 months * After receiving the toothpaste at the baseline visit, subjects will visit the clinic at 3 months and 6 months for additional data collection.
Inclusion Criteria: * Understands and is willing to sign an Informed Consent, approved by the local Ethics Committee. * Female or male, ages 18-95 years old (inclusive) * Systemically healthy. * Presence of at least three evaluable teeth in each quadrant. * Moderate gingival inflammation, with at least a 10% of bleeding on probing (BOP) will be required together with moderate level of plaque. * No Grade 3 Tooth Mobility * Treated stage II or III periodontitis patients, whose active treatment has finalized more than 6 months before. Stage II - Interdental clinical attachment level (CAL) at the…
Participants will use arginine toothpaste twice daily (morning and evening) for 6 months. Sterile paper will be used to collect plaque from below the gum line at baseline, 3 months, and 6 months.
Participants will use fluoride toothpaste twice daily (morning and evening) for 6 months. Sterile paper will be used to collect plaque from below the gum line at baseline, 3 months, and 6 months.
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