Voyager Therapeutics
VY1706 first in human study in early Alzheimer's Disease is a multicenter dose escalation study
Inclusion Criteria: * Male or female participants aged 55 to 80 years (inclusive) at Screening or aged 30 to 80 years (inclusive) if presence of a historically documented dominantly inherited mutation associated with monogenic AD. * Clinical diagnosis of mild cognitive impairment (MCI) due to AD or mild AD with MMSE 18-30 and CDR Global score of 0.5-1. * Evidence of amyloid and tau pathology consistent with AD diagnosis by both: * Apart from the clinical diagnosis of early AD, participant must be in good health as determined by the Investigator. * If the participant is receiving an approved s…
Low dose
Mid Dose
High dose
Anti-AAV9 Total Antibody (TAb) Assay
Arctuva estimate
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