Fox Chase Cancer Center
This study compares two methods of prescribing parenteral nutrition (PN) in adults with cancer who are unable to meet nutritional needs by oral or enteral intake.
This is a single-center, randomized, open-label pilot study enrolling 50 adult oncology patients requiring PN (parenteral nutrition). Participants are randomized to weight-based dosing or indirect calorimetry-guided dosing. Outcomes include feasibility, acceptability, changes in PN prescription, adverse events, quality of life, and survival.
Inclusion Criteria: * Adults aged ≥18 years * Diagnosis of cancer * Requirement for PN ≥1 week * Ability to provide informed consent * English-speaking Exclusion Criteria: * Hospice enrollment * Mechanical ventilation * Chest tube or drain * Continuous renal replacement therapy * Supplemental oxygen
Q-NRG + metabolic monitor
Parenteral nutrition dosed using standard weight-based equations.
Arctuva estimate
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