A Multicenter, Open-Label Extension Study of the Long-Term Safety of Vonaprument (ANX007) Administered by Intravitreal Injection in Participants With Dry Age-Related Macular Degeneration With Geographic Atrophy

Annexon, Inc.

Summary

The primary purpose of the study is to assess the long term safety of intravitreal (IVT) injections of vonaprument.

Eligibility

Age range: 50+ years
Sex: All
Healthy volunteers: No

Detailed criteria

Inclusion Criteria: * Participants with a diagnosis of dry AMD with GA who completed the Phase 3 ARCHER II study (NCT06510816) and who had not permanently ceased receiving the assigned masked treatment (IVT or Sham administration) at/before the ARCHER II Month 24 Visit. Exclusion Criteria: * Any event or condition arising during the ARCHER II study that would put the participant in danger or lead to undue harm by participating in this OLE study.

Interventions

Drug
Vonaprument
Form: solution for injection; Route of Administration: IVT injection

Locations (7)

Retina Group of Florida
Sarasota, Florida
Retina Vitreous Associates of Florida
St. Petersburg, Florida
Cumberland Valley Retina Consultants
Hagerstown, Maryland
Mid Atlantic Retina Specialists
Hagerstown, Maryland
Retina Research Institute at New England Retina Consultants
Springfield, Massachusetts
Asheville Eye Associates - Retina Division
Asheville, North Carolina