AdventHealth
The goal of this clinical trial is to determine the serum ferritin level and hematocrit level in very preterm infants receiving donor breast milk(DBM) with an early iron supplementation protocol . The main questions it aims to answer are: Does earlier iron supplementation provide increased ferritin levels at 14 and 28 days of life in subjects fed primarily donor breast milk? Iron supplementation will be implemented when the infant achieves 80ml/kg/day of enteral feeds, as contrasted to the current protocol of full feeds (140 to 160ml/kg/day), the latter usually by Day 14 of life. At day of life(DOL) 14 (± 4 days), a blood sample will be obtained for serum ferritin determination. Similarly, a second blood draw would be performed at day of life 28 (± 4 days) or prior to discharge, whichever comes earlier
In preterm and low birth weight (LBW) infants, moderate-certainty evidence indicates that feeding with commercial infant formula compared with donor breast milk (DBM), either as a supplement to maternal expressed breast milk (MBM) or as a sole diet, results in higher rates of weight gain, linear growth, and head growth but is associated with a higher risk of developing necrotizing enterocolitis (NEC)1-5. Despite the decreased incidence of NEC, DBM has been shown to be inferior to MBM in terms of overall growth. This is attributed to the fact that DBM contains significantly less protein, fat an…
Inclusion Criteria: * 1\. All preterm infants born between 29.0-32.6 weeks of gestational age and admitted to the NICU at Advent Health for Children 2. Infants likely to be receiving DBM between 5 to 14 days of life 3. Infants receiving \>50% of the feeding volume by DBM will be considered to have received DBM. Exclusion Criteria: 1. Death prior to completion of participation or extremis with likelihood of death prior to completion of participation in the study 2. Blood transfusion as determined by clinical team during the study 3. Major congenital anomaly or genetic syndrome and major surg…
Dietary Supplement
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