Banner Health
The goal of this study is to assess the overall success of energy delivery during treatment using the ultrasound guided microwave ablation device in patients with locally advanced, unresectable, or metastatic cancer. Secondly, this study aims to explore the procedural/clinical safety of treatment with the device and the antitumor effect following treatment with the device.
Inclusion Criteria: * Male or female ≥18 years of age * Willing and able to provide written informed consent * Histologically confirmed locally advanced, unresectable or metastatic cancer (Stage III or IV) * At least 1 tumor that is indicated for MWA, and the location of target tumor must be accessible via EUS through the gastric wall (eg, pancreas, liver, etc). * The tumor(s) must be ≥1 cm in diameter Exclusion Criteria: * Participant is a candidate for upfront resection of pancreatic cancer * Participation in another clinical trial that involves local ablation or any other local therapy t…
The rationale of this study is to generate preliminary data on the functionality and safety of Creo's MicroBlate™ Fine device when used under EUS guidance. The results generated from this study will inform any decisions regarding subsequent pivotal trials and may support the integration of this approach into clinical practice for anatomically challenging tumors.