University of Miami
The purpose of this study is to directly compare the efficacy of suzetrigine vs. oxycodone+acetaminophen vs. alternating acetaminophen/ibuprofen in controlling post-operative pain after the following nail unit procedures.
Inclusion Criteria: * All patients age 18+ able to understand and provide written consent in English or Spanish who present to Dr. Brian Morrison's clinic at the University of Miami and are undergoing a nail unit procedure. Exclusion Criteria: * Patients under the age of 18 or adults unable to consent. * Patients who are pregnant or incarcerated.
Participants will receive two 50 mg oral tablets on day 1, followed by 50 mg oral tablets every 12 hours for 5 days
Participants will receive oral oxycodone 5 mg/acetaminophen 325 mg (Percocet®) as a fixed-dose combination tablet every 6 hours for 5 days, beginning on the day of the nail procedure.
Participants will receive acetaminophen 650 mg orally every 6 hours, alternating with ibuprofen, for 5 days beginning on the day of the nail procedure.
Participants will receive ibuprofen 400 mg orally every 6 hours, alternating with acetaminophen, for 5 days beginning on the day of the nail procedure.
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