University of Alabama at Birmingham
The purpose of this study is to determine whether a ketogenic diet, provided as tube feeding, compared with a standard hospital tube feeding, is safe and feasible and helps preserve muscle mass and improve metabolic health in adults aged 55 years and older hospitalized with traumatic injury.
Inclusion Criteria: * Age 55 years and older * Traumatic injury * Expected to survive and at least 10-day stay in the hospital * Expected to be enterally fed for at least 10 days * Willingness to be randomized to either treatment group * Willingness to participate in all study procedures Exclusion Criteria: * Failure to provide informed consent * Moribund * Vegeterian/vegan * Diagnosed dementia * Hip fracture, hip or knee replacement, or spinal surgery within past 4 months * Simultaneous participation in another intervention trial
The ketogenic feeding will have a macronutrient composition of approximately 10% energy from carbohydrates, 25% energy from protein, and 65% energy from fat.
The participants will receive standard hospital care feeding.
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