St. Jude Children's Research Hospital
This study aims to develop a more comprehensive approach to monitoring fluid status in patients undergoing stem cell transplantation by combining conventional methods with a bioimpedance device.
Primary Objective: * To evaluate the feasibility of obtaining serial bedside bioimpedance analysis (BIA) measurements during the initial hematopoietic stem cell transplantation hospitalization, defined by the proportion of scheduled assessments successfully completed at prespecified time points, and to descriptively characterize within-patient longitudinal changes in total body water (TBW), extracellular water (ECW), and intracellular water (ICW). Secondary Objective: * To compare BIA-derived fluid measurements with routine clinical fluid assessment methods (e.g., daily weights and intake/o…
Inclusion Criteria: * Ages 6-21 years planned to undergo allogeneic or autologous HSCT for any indication with any preparative regimen. Exclusion Criteria: * Pacemaker implantation due to incompatibility with the bioimpedance device * Lack of agreement from the primary HSCT physician. * Inability or unwillingness of the research participant and/or legal guardian/representative to provide written informed consent.
Routine bioimpedance device measurements will be taken at specific times during the patient's initial hospitalization after the transplant. They will be performed alongside regular nursing assessments in the patient's hospital room.
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