A Phase 1, First-in-human, Randomized, Single-blind, Active-controlled, 2-arm, Parallel-group, Single Ascending Dose Study to Evaluate the Safety and Tolerability of OPF-110 in Healthy Adult Participants.

Inclusion Criteria: 1. Capable of giving signed informed consent , which includes compliance with the requirements and restrictions listed in the Informed Consent Form (ICF) and in this protocol. 2. Healthy participants aged 18 to 64 years (inclusive) at the time of signing the ICF. 3. Participants who have body mass index (BMI) of ≥18.5 and \<30.0 kg/m2 at Screening. 4. Nonsmoker or occasional smokers (ie, smokes ≤10 cigarettes \[or equivalent\] per day) or participants who have not used nicotine-containing products within 3 months prior to Day 1, based on participants self-reporting and abi…