Eight Sleep Inc.
This study examines whether two continuous weeks of overnight active temperature regulation (via the Eight Sleep Pod) use affects gut microbiome composition, inflammation, and the body's daily temperature and blood pressure rhythms in postmenopausal women and age-matched men with self-reported poor sleep.
The goal of this study is to test whether improved sleep quality and stronger circadian patterns can improve gut health and decrease inflammation among postmenopausal women and men of a similar age. Previous research has documented the beneficial health outcomes from improved sleep quality. However, current research has yet to look at how overnight active temperature regulation can improve gut and cardiometabolic health. We will use the Eight Sleep Pod, a temperature-regulated mattress cover, to control bed temperature overnight. We want to see if this improves the community of bacteria in you…
Inclusion Criteria: All Cohorts * 45 years of age or older * Self-reported poor sleep quality: PSQI score greater than 5 * Within 1.5 hours driving of the Greater Boston area * Have never used an Eight Sleep Pod (or similar device) ever * Post-enrollment hsCRP ≤ 10 µg/mL at Preparation Period blood panel. If Preparation Period hsCRP \> 10 µg/mL: triggers clinical review on a case by case basis; hard exclusion applies only at \> 30 µg/mL Weight ≥ 88 lbs * No MRI scheduled during the study period or within 1 week after study conclusion * No acute illness, injury, or dental procedure/cleaning wi…
Water-perfused mattress cover actively regulating temperature overnight, temperature will be ON during Condition 1 and OFF during Condition 2.
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