Northwell Health
Dietary patterns and physical inactivity common in Western societies have been associated with chronic low-grade inflammation and an increased risk of non-communicable health conditions. Fruits and vegetables contain polyphenols and other bioactive compounds that may have antioxidant and anti-inflammatory properties and may influence inflammatory biomarkers. This study will evaluate the effects of increased consumption of a fruit juice on inflammatory biomarkers and exercise capacity in adults with mildly elevated inflammation. Approximately 40 participants will be randomly assigned to consume one of two fruit juice interventions daily for approximately 2 weeks. Changes in C-reactive protein (CRP) and exercise capacity, assessed using a 6-minute walk test, will be evaluated before and after the intervention and compared between the two groups.
Industrialization and changes in dietary and physical activity patterns have contributed to differences in the health conditions experienced by populations in Western societies. Chronic, non-communicable conditions, many of which are associated with low-grade inflammation, are now major contributors to morbidity and mortality. Dietary patterns characterized by high consumption of refined carbohydrates, sugars, salt, and animal fats and relatively low consumption of fruits, vegetables, fiber, and plant-derived phytochemicals may contribute to an inflammatory state. Similarly, low levels of phys…
Inclusion Criteria: 1. Participants ages 18-65 years old 2. Physically and cognitively able to provide informed consent. 3. Asymptomatic. 4. Prior confirmed high normal or mild elevation of CRP (1.5- 9.9 mg/L) 5. Able to perform a 30-second sit-to-stand test, a 6-minute walk test and a test of grip strength. 6. Amenable to finger stick blood collection to determine CRP. 7. Willing to consume 2- 8 oz juice beverages per day, containing 25 grams of sugar each, for 2 weeks. Exclusion Criteria: 1. Diagnosis of: 1. Obstructive coronary artery disease (CAD). 2. Currently or recently having…
Commercially available fruit juice administered as the dietary intervention. Participants will consume the assigned juice daily for approximately 2 weeks according to the study protocol. The specific product identity is not disclosed to participants as part of the study design.
Commercially available fruit juice administered as the investigational dietary intervention. Participants will consume the assigned juice daily for approximately 2 weeks according to the study protocol. The specific product identity is not disclosed to participants as part of the study design.
Arctuva estimate
Verify or correct the compensation shown for this listing.