The University of Texas Health Science Center, Houston
The overall goal is to evaluate the effectiveness of different stimulation protocol of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) in managing neuropathic pain after spinal cord injury (SCI).
Inclusion Criteria (SCI subjects): * has a history of SCI \> 1 year; * has a DN4 (Douleur Neuropathique en 4 questions)\* score of 4 or greater; * has an average pain score of 4 or more * has neuropathic pain \>3 months; * is between 22 to 80 years of age; * is stable on oral pain medications at least one month (no change in frequency and dosing of pain medications); * is able to tolerate BreEStim treatment for 1 minute. Exclusion Criteria (SCI subjects): * is on a mechanical ventilator; * is currently having active urinary tract infection (UTI); * does not have any residual sensation in th…
During the Single-pulse BreEStim Treatment session, participants will remain relaxed while breathing is monitored using a nasal cannula. Surface electrodes will be placed over the median nerve at the wrist or another selected peripheral nerve. A single-pulse electrical stimulation will be synchronized with voluntary breathing and delivered at an individually tolerated intensity for approximately 30 minutes.
During the Multiple-pulse BreEStim Treatment session, participants will remain relaxed while breathing is monitored using a nasal cannula. Surface electrodes will be placed over the median nerve at the wrist or another selected peripheral nerve. Multiple-pulse electrical stimulation will be synchronized with voluntary breathing and delivered at an individually tolerated intensity for approximately 30 minutes.
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