University of Maryland, Baltimore
This study will compare the cardiovascular effects of continued smoking with those of e-cigarette (EC) use among older adults with hypertension. Using both laboratory and real-world measurements, this study will be the first to examine the relative cardiovascular impacts of smoking and EC in a patient population at high risk of smoking-related disease progression.
Tobacco smoking remains a leading cause of chronic disease, premature death, and healthcare costs in the United States. Older adults bear the greatest burden of smoking-related cardiovascular disease (CVD), which is the leading cause of smoking-related mortality. Yet this age group remains significantly underrepresented in tobacco research and is also the only age group not experiencing a decline in smoking prevalence. Hypertension, a key factor connecting smoking to myocardial infarction, stroke, and heart failure, is especially common among older adults who smoke. Although e-cigarettes (ECs)…
Inclusion Criteria: * Age 50 years or older. * Currently smokes 5 or more combustible tobacco cigarettes per day and has smoked at this level for at least 1 year, based on self-report. * Expired-air carbon monoxide level ≥8 parts per million (ppm), confirming recent cigarette smoking. * Average screening/baseline systolic blood pressure ≥130 mm Hg or average screening diastolic blood pressure ≥80 mm Hg. * Able and willing to provide informed consent and complete the study procedures, including in-person visits, two 14-day study periods, daily check-ins, and use of study equipment. * If able t…
E-cigarettes that are FDA-authorized will be provided to participants in their preferred flavor (tobacco or menthol) and strength.
Participants own brand cigarette
Arctuva estimate
Actual pay is set by the research site.
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