Ohio State University
The purpose of this study is to compare latency (prolongation of pregnancy from diagnosis till delivery) in patients with hypertensive disorders of pregnancy (HDP) with severe features \< 34 weeks gestational age (GA), undergoing expectant management between tight and permissive blood pressure (BP) groups.
Inclusion Criteria * Pregnant individuals * Age ≥ 18 years old * HDP with severe features * Planned inpatient admission for expectant management until delivery * GA 24 - ≤ 32 weeks GA * Singleton, non-anomalous fetus * Anticipated delivery at the study institution Exclusion criteria: * HDP with severe features \> 32 weeks gestation at the time of admission * Poorly controlled preexisting chronic hypertension on ≥2 oral antihypertensive medications * Preexisting CKD with serum creatinine \> 1.0 * Contraindications to expectant management of preeclampsia with severe features per ACOG (attache…
In either group, sustained (persistent high blood pressures SBP ≥ 160 mm Hg and/or DBP ≥ 110 mmHg) are treated acutely with intravenous or rapid acting oral medications, per American College of Obstetricians \& Gynecologists (ACOG) recommendations.
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