University of Alabama at Birmingham
This study will compare three different full-thickness skin graft sizes (90%, 100%, and 110% of the surgical defect size) in patients undergoing reconstruction of nasal or ear surgical defects. Participants will be randomly assigned to one of the three graft sizes and followed for 12 months. The study will evaluate scar quality, graft contraction, cosmetic outcomes, patient satisfaction, and complications to determine whether graft size affects healing and final appearance.
Inclusion Criteria: * Age 18 years or older * Undergoing dermatologic surgery resulting in a nasal or auricular defect appropriate for full-thickness skin graft reconstruction * Able to provide informed consent * Willing and able to complete required study follow-up and photography Exclusion Criteria: * Age younger than 18 years * Prisoners * Pregnant women * Non-English-speaking individuals * Concurrent enrollment in another ongoing interventional trial * UAB students or employees * History of keloids or clinically significant hypertrophic scarring * Immunosuppression judged to significant…
Participants will undergo full-thickness skin graft reconstruction using a graft harvested at 90%, 100%, or 110% of the measured recipient defect dimensions, according to randomized treatment assignment. Graft harvest, preparation, inset, fixation, donor-site selection, and postoperative wound care will otherwise follow routine clinical practice.
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