Weill Medical College of Cornell University
This study is designed to evaluate the effectiveness and safety of Vinoperfect, a skin-brightening serum, for treating post-inflammatory hyperpigmentation (PIH), or dark spots that can develop after acne, in participants with Fitzpatrick Skin Types IV-VI (medium to deep skin tones). The study will assess Vinoperfect as part of a comprehensive skincare routine that includes cleansing, treatment, moisturization, and protection from sunlight.
This is a single-center, open-label trial designed to assess the efficacy and tolerability of a skin brightening serum in individuals with skin of color who are diagnosed with acne-induced Post-Inflammatory Hyperpigmentation on the facial skin. The study will be conducted at a single site, enrolling male and female participants from a range of ethnic/racial backgrounds, all with Fitzpatrick Skin Types IV-VI. Study participation will last for 12 weeks.
Inclusion Criteria: 1. Male or female participants aged ≥18 years. 2. Participants with Fitzpatrick Skin Types IV, V, or VI. 3. Participants of any ethnicity. 4. Presenting with moderate to severe post-inflammatory hyperpigmentation, as determined by a PAHPI score of 8 or higher. 5. Presenting with history or presence of mild acne, as indicated by a Global Acne Severity Score of 2 or lower (GEA ≤ 2). 6. Capable of understanding and communicating in English, and willing to provide written informed consent to participate in the study. 7. Willing to comply with study requirements, including atte…
Participants will undergo a standardized twice-daily skincare regimen for 12 weeks. In the morning, participants will cleanse their face, apply the Vinoperfect Brightening Serum, apply moisturizer, and then apply SPF 50+ sunscreen. In the evening, participants will cleanse their face, apply the Vinoperfect Brightening Serum, and apply moisturizer.
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