Calypta Systems, Inc.
This randomized trial tests whether an online guide combining short evidence cards with an AI-guided conversation increases flu-vaccination intention among US adults who haven't decided whether to get a flu vaccine this season. Participants recruited through Prolific are randomly assigned to the flu guide or to a structure-matched guide about everyday accident safety. The primary outcome is self-rated likelihood of getting a flu vaccine this season (1-7), asked immediately after the session. Participants are asked at about 2 and 8 weeks whether they have been vaccinated. The study is powered for the intention outcome but not for vaccination. For vaccination, it estimates the effect, the base rate, and follow-up response, to size a later, larger trial.
In a prior randomized trial by the same investigator, a similar intervention (evidence cards followed by an AI-guided motivational-interviewing conversation) raised MMR vaccination intention among hesitant parents by about one point on a 1-7 scale relative to an active control (Forman 2025, PsyArXiv, doi:10.31234/osf.io/5kteh\_v1). This study tests whether the effect transfers to a different decision and population: adult seasonal flu vaccination. Design: two-arm, parallel, 1:1 randomized trial conducted entirely online. Participants are US adults on Prolific (approval rate ≥ 99%, at least 25…
Inclusion Criteria: * US resident, age 18 or older, Prolific approval rate ≥ 99% and at least 25 previous submissions * Answers "Probably", "Unsure", or "Probably not" to planning to get a flu vaccine in the next few months * Consents to participate Exclusion Criteria: * Already vaccinated against flu this season ("Already done this year") * Baseline intention of 7 ("Definitely yes") * Took part in the feasibility pilot
Online guide with 12 evidence cards on seasonal flu and flu vaccines (including an interactive simulation of flu risk), with per-card minimum reading times, followed by a text or voice conversation with an AI model instructed to use motivational-interviewing techniques and to draw on curated, cited sources. The session takes about 10 to 20 minutes.
Online guide with 12 evidence cards on everyday accident avoidance (driving, falls, and smoke and carbon-monoxide alarms; including an interactive seatbelt simulation), with matched minimum reading time, followed by an AI conversation under the same rules. The session takes about 10 to 20 minutes.
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