Leigh R. Hochberg, MD, PhD.
In this study, the investigators aim to continue the development of a brain-computer interface (BCI) to help restore speech for stroke survivors with agrammatic aphasia, a language disorder that affects the ability to speak.
One in four adults will have a stroke in their lifetime. When the blood flow to the brain is blocked or reduced, brain cells get deprived of oxygen. This might impact language areas in the brain and lead to aphasia. The goal of this project is to advance the methods by which people with aphasia can help develop and by using an intracortical brain-computer interface (iBCI) restore communication that may serve as a rehabilitation device.
Inclusion Criteria: * Inclusion Criteria: * Clinical diagnosis of spinal cord injury, brainstem stroke, muscular dystrophy, amyotrophic lateral sclerosis, or other motor neuron disorders * Complete or incomplete tetraplegia (quadriplegia) * Prior enrollment in BrainGate2 clinical trial (NCT00912041) Exclusion Criteria: * Visual impairment such that extended viewing of a computer monitor would be difficult even with ordinary corrective lenses * Chronic oral or intravenous steroids or immunosuppressive therapy * Other serious disease or disorder that could seriously affect ability to particip…
Placement of the BrainGate2 sensor(s) for restoration of speech
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