Memorial Sloan Kettering Cancer Center
The purpose of this study is to find out which of three standard skin care approaches works best to prevent a skin reaction called radiation dermatitis (redness, irritation, or breakdown of the skin) in people receiving radiation therapy after mastectomy.
Inclusion Criteria: * Patients must have pathologically confirmed breast cancer. * Patients will have an assigned sex of female at birth. * Patients will have undergone mastectomy without breast reconstruction surgery or with immediate reconstruction using one or more of an expander, implant, or flap-based approach. * Patients will have pathologic stage T1-3 N0-1 M0 disease with indication for comprehensive post-mastectomy radiotherapy to the ipsilateral chest wall and regional lymph node basins (axilla, SCV, IMN). * Patient/LAR willing to sign and date consent form * Age ≥ 18 * ECOG Performa…
Mometasone Furoate 1% Cream is a topical corticosteroid cream
Mepitel Film is a transparent film with a contact layer with silicone adhesion.
Bacterial decolonization (BD) regimen involves a 5 day regimen of twice-daily intranasal mupirocin and chlorhexidine body cleansing
Bacterial decolonization (BD) regimen involves a 5 day regimen of twice-daily intranasal mupirocin and chlorhexidine body cleansing