University of Florida
This is a randomized, single-center phase 2 study comparing early versus delayed oral feeding after total laryngectomy. Dysphagia-related outcomes will be assessed using the MDADI preoperatively, and on postoperative days 14 (±7) and 30 (±7). Secondary outcomes include fistula requiring intervention, surgical site infection, wound dehiscence, oral feeding tolerance, feeding tube duration, nasogastric tube removal, length of stay, PSS-HN scores, and patient-reported oral rehabilitation.
Inclusion Criteria: * Subjects who have elected to undergo total laryngectomy surgery * Subjects receiving free-tissue transfer regardless of indication for total laryngectomy * Subjects who are English and/or Spanish speaking. * Written informed consent obtained from the subject and the subject agrees to comply with all the study-related procedures. Exclusion Criteria: * Subjects who have undergone prior major head and neck surgery or radiation therapy involving the larynx (also referred to as surgical salvage patients). * History of severe dysphagia or with current enteral feeding needs *…
Subjects will begin oral intake post-op day 1
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