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27,273 recruiting studies available now

A Phase I Trial of Intraperitoneal Mesothelin-Targeted CAR T Cell Therapy in Patients With Mesothelin-Positive Esophagogastric Adenocarcinoma With Peritoneal Carcinomatosis or Malignant Peritoneal Mesothelioma

Participants will have a sample of their white blood cells, called T cells, collected using a procedure called leukapheresis. The collected T cells will be sen…

Mesothelin PositiveMesothelin-Expressing TumorsEsophageal Adenocarcinoma+5 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT06623396

Phase 1

MRI-Guided Adaptive Radiation Therapy for Organ Preservation in Rectal Cancer

This study is a prospective, open-label, phase I design.

Rectal Adenocarcinoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Medical College of WisconsinNCT04808323

Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

Background: A germline mutation is a change to a person s genes that is carried through their DNA. These mutations can be passed on from parents to their offs…

Familial CancerBRCA1-Associated Protein-1 (BAP1) MutationsTumor Predisposition Syndrome (TPDS)+1 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT04431024

Phase 2

Imaging and Biopsy of People With HIV-1 Undergoing Analytic Treatment Interruption

Background: Human immunodeficiency virus (HIV) infects CD4 T cells. There is no cure for HIV. People with HIV need to take daily medications called antiretrov…

HIV

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT05419024

Observational

A Prospective, Single Center Clinical Trial Assessing the Efficacy and Safety of the NaviCam Patency Capsule to Verify Gastrointestinal Patency

Participants included in this study will first swallow a patency capsule and then undergo an abdominal X-ray scan within 30 hours after swallowing the capsule …

Intestinal StrictureCrohn DiseaseNSAID (Non-Steroidal Anti-Inflammatory Drug) Induced Enteropathy+1 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

AnX Robotica Corp.NCT07649720

Observational

Investigating Changes in Premonitory Urges During Habit Reversal Training

The primary aim of this study is to learn more about premonitory urges (PU) when using Habit Reversal Training (HRT) to treat tics. The main focus of this stu…

TicsTourette DisorderTourette Syndrome in Children+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of UtahNCT06825520

Phase 1

A Phase 1/2, Open-Label, Multicenter, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics/Pharmacodynamics, and Preliminary Efficacy of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

The study has consists of two parts, a dose escalation part (Part 1) and a dose selection optimization part (Part 2). The primary objectives of this study are …

Locally Advanced/Metastatic Solid Tumors

Estimated

~$150 – $4,200

Actual pay is set by the research site.

InSilico Medicine Hong Kong LimitedNCT06414460

Lidocaine Infusion As A Treatment Modality For Headache Following Non-Traumatic Subarachnoid Hemorrhage: A Prospective, Single-Center, Observational Cohort Study

The goal of this observational study is to evaluate intravenous lidocaine efficacy and safety in treating headache following non-traumatic subarachnoid hemorrh…

Subarachnoid; Hemorrhage, NontraumaticHeadache

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Kansas Medical CenterNCT06582810

Observational

Confirmatory Study of Substantial Equivalence Between cureVision cV and MolecuLight i:X in Detecting Bacterial Burden in Wounds

The study aims to demonstrate the substantial equivalence of the cureVision cV system's performance in detecting moderate to high bacterial loads in direct com…

DFUVLUSurgical Wound+2 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Capsicure, LLCNCT07611318

Phase 4

A Phase 4, Open Label Study to Assess Descriptive Classification of Pruritus Over Time With Roflumilast 0.15% Cream in Patients With Atopic Dermatitis

This study is being done to obtain descriptive classifications of pruritus using a patient directed survey system and assess change in pruritus over time in pa…

ITCHAtopic Dermatitis

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Integrative Skin Science and ResearchNCT07560618

Observational

Improving TMJ Joint Positioning and Accuracy With Therapeutic Splint Fabrication Using a Dental Compass While Reducing Radiation Exposure: A Cohort Comparison

This study is being performed to determine if the use of the Dental Compass Articular and its software will produce therapeutic splints for TMD accurately and …

Temporomandibular Joint Syndrome

Estimated

~$10 – $750

Actual pay is set by the research site.

Dr. Dean Reeves ClinicNCT06619574

Phase 1

An Integrated Phase I/II, Multicentre, Double-blind, Randomised, Dysport and Placebo-controlled, Dose Escalation and Dose-finding Study to Evaluate the Safety and Efficacy of IPN10200 in the Treatment of Adult Upper Limb Spasticity.

The purpose of the study is to assess the safety and efficacy of increasing doses of Corabotase (also known as IPN10200) with the aim to evaluate the Pharmacod…

Spasticity

Estimated

~$150 – $4,500

Actual pay is set by the research site.

IpsenNCT04752774