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27,295 recruiting studies available now

Randomized Phase III Trial of Multimodality Therapy Versus Standard of Care Systemic Therapy in HER2 Positive (HER2+) De Novo (AJCC Stage IV) Oligometastatic Breast Cancer With Response to Initial Chemotherapy

This phase III trial evaluates the effect of adding locoregional therapy (surgery and radiation) and metastasis-directed stereotactic body radiation therapy (S…

Anatomic Stage IV Breast Cancer AJCC v8Metastatic HER2-Positive Breast CarcinomaOligometastatic Breast Carcinoma

Estimated

~$50 – $2,250

Actual pay is set by the research site.

SWOG Cancer Research NetworkNCT07578116

Observational

Targeting Vascular Mechanisms of Functional Outcomes Via Home-based Exercise Training Among Persons With Multiple Sclerosis Who Have Hypertension

The goal of this study is to determine if 12 weeks of cycling exercise training at home will improve three parameters: 1) blood pressure, 2) cognition, and 3) …

Multiple SclerosisHypertension

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Massachusetts, BostonNCT06554340

Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke

The goal of this observational study is to use a genetic test to help doctors prescribe the most effective medications after a patient has a stroke. One type o…

Ischemic StrokeCYP2C19 Polymorphism

Estimated

~$10 – $750

Actual pay is set by the research site.

University of VirginiaNCT06292117

Phase 2

A Randomized Controlled Trial to Study the Effects of One-time Intra-operative Dosing of Methadone During Laparoscopic or Robotic Hysterectomy in Reducing Opioid Prescription.

Currently, there is a nationwide epidemic of opioid abuse and overdose deaths. One source of excess opioids is overprescribing in the postoperative period. Thi…

Fibroid Uterus

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Johns Hopkins UniversityNCT06536517

Waveform Capnography and Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults

This study will compare the sensitivity and specificity of waveform capnography versus colorimetric carbon dioxide detection to identify tracheal placement of …

Acute Respiratory Failure

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Brian DriverNCT06934876

Observational

Reestablishing Sleep and Circadian Alignment in Medically Critically Ill Patients Via a Mechanistic Randomized Controlled Trial (RCT) of an Intensive Care Unit (ICU) Sleep Chronobundle

More than 5 million patients are admitted to the intensive care unit every year in the United States; most of these patients experience profound sleep and circ…

Critical IllnessSleep DeprivationCircadian Rhythm Sleep Disorder, Unspecified

Estimated

~$10 – $750

Actual pay is set by the research site.

Yale UniversityNCT05551325

Collection of Peripheral Blood Samples From Donors and Recipients of Blood and Marrow Transplants for Laboratory Research in Immune Reconstitution

This specimen collection lab protocol will allow the investigators to prospectively study immune reconstitution in patients being treated for hematologic disor…

Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

University of MiamiNCT02129543

Phase 1

A Multi-Center Pilot/Phase I and Phase II Clinical Trial of NG101m Adjuvant Therapy in Newly Diagnosed Glioblastoma Patients

The purpose of this clinical trial is to evaluate the addition of NG101m adjuvant therapy to standard of care treatment of glioblastoma multiforme. All subject…

Glioblastoma Multiforme

Estimated

~$150 – $4,500

Actual pay is set by the research site.

NeuGATE TheranosticsNCT04373785

Phase 2

MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial

This study is being done to determine if early administration of Midodrine can improve outcomes by maintaining a higher mean blood pressure off of intravenous …

SepsisLow Blood Pressure

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Mayo ClinicNCT06319248

A 90 Day Observational Study as an Extension to the Phase 3, Open Labeled, Exploratory Study of RELiZORB to Evaluate Safety, Tolerability, and Nutrient Absorption in Children With Short Bowel Syndrome Who Are Dependent on PN

Children with inadequate intestinal absorption due to loss of large amounts of small bowel require intravenous nutrition (feeding through the vein) to sustain …

Short Bowel SyndromeMalabsorption

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston Children's HospitalNCT05635747

Phase 3

Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction, SPIRRIT-HFPEF

Heart failure with preserved ejection fraction (HFPEF) is common and deadly but without therapy. Inconclusive studies such as TOPCAT (Treatment of Preserved Ca…

Heart Failure With Preserved Ejection Fraction

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Uppsala UniversityNCT02901184

A Prospective Study of Recovery Mechanisms in Heart Transplant Eligible Patients With Cardiogenic Shock on Impella 5.5 Support

This observational study is being done to learn more about heart attack recovery in patients supported with the Impella 5.5 left ventricular assist device (LVA…

Heart FailureCardiomyopathy

Estimated

~$10 – $750

Actual pay is set by the research site.

Columbia UniversityNCT06800716