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27,306 recruiting studies available now

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Phase 2

A Phase 2, Open-Label Study to Evaluate the Safety and Efficacy of Budoprutug (TNT119) in Subjects With Primary Membranous Nephropathy (PMN)

To evaluate the safety and tolerability of three dose regimens of budoprutug in subjects with PMN

Primary Membranous Nephropathy

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Climb Bio, Inc.NCT07096843

Phase 2

A Two-stage Double-blind, Randomized, Placebo-controlled Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.

The main purpose of this study in participants with PIK3CA-mutated LyM is to assess the change in radiological response and symptom severity upon treatment wit…

Lymphatic Malformations

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Novartis PharmaceuticalsNCT05948943

Phase 2

A Clinical Trial of Resistant Potato Starch for Gut MDRO Decolonization

Multidrug-resistant organisms (MDROs) cause serious infections that are difficult to treat, leading to increased morbidity and mortality, longer hospital stays…

Clostridium InfectionsMethicillin-resistant Staphylococcus Aureus (MRSA)Vancomycin-Resistant Enterococci+2 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT07792915

ObservationalRemote eligible

Percepta for Cognitive Optimization: A 6-Month Randomized Controlled Trial With Neurocognitive, Wearable, and Participant-Reported Outcomes in Adults With Mild Cognitive Impairment

This Phase 1, randomized, double-blind, placebo-controlled trial evaluates the cognitive and neurophysiological effects of a dietary supplement containing cat'…

Mild Cognitive Impairment (MCI)Memory

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Cerebrum DAO AssociationNCT07612449

Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders

The specific aim of this project is to validate clinical tests to be used as outcome measures in studies of mTBI-related vision problems.

MTBI - Mild Traumatic Brain Injury

Estimated

~$10 – $750

Actual pay is set by the research site.

Salus UniversityNCT07282691

Observational

Reducing Urban Cervical Cancer Disparities Using a Tailored MHealth Intervention to Enhance Colposcopy Attendance

This study uses a hybrid Type 1 effectiveness-implementation trial to operationalize and assess the efficacy of the Health Enhancement Resource System (HERS) i…

Cervical CancerPapilloma Viral Infection

Estimated

~$10 – $750

Actual pay is set by the research site.

Fox Chase Cancer CenterNCT06416150

Phase 1

An Open-Label, Phase 1, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Intravenous DCR-PDL1 in Adults With Solid Tumors

The study will evaluate the safety, tolerability, and pharmacokinetics of intravenous DCR-PDL1 in adults with solid tumors. Participants will be enrolled in on…

Solid Tumors, Adult

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Dicerna Pharmaceuticals, Inc., a Novo Nordisk companyNCT06504368

Prospective Follow-up of Patients Undergoing Instrumented Thoracic and Lumbar Arthrodesis Supplemented by the Implanet Jazz System TM.

Establish a data repository of patients who have undergone single, two-, or three-level lumbar instrumented arthrodesis procedures supplemented by the Implanet…

SpondylolisthesisSpinal StenosisDegenerative Disease

Estimated

~$10 – $675

Actual pay is set by the research site.

Francis FarhadiNCT05366140

Observational

Probing the Functional and Behavioral Impact of Precision Circuit Modulation in Neuropsychiatric Diseases

Repetitive transcranial magnetic stimulation (rTMS) is a way of non-invasively stimulating specific brain networks and is an established treatment for Major De…

Major Depressive Disorder

Estimated

~$10 – $750

Actual pay is set by the research site.

Massachusetts General HospitalNCT05523817

Phase 2

Phase II, Open-Label, Prospective Study of T Cell Receptor Alpha/Beta Depletion (A/B TCD) Peripheral Blood Stem Cell (PBSC) Transplantation for Children and Adults With Hematological Malignancies

This is a phase II, open-label, prospective study of T cell receptor alpha/beta depletion (TCR α/β TCD) peripheral blood stem cell (PBSC) transplantation for c…

Hematologic MalignancyAcute LeukemiaRemission+21 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Phase 4

Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients

The goal of this randomized clinical trial is to learn if the use of a low-dose nonsteroidal anti-inflammatory drug (NSAID), ketorolac, reduces the rate of chr…

Orthopaedic TraumaChronic Opioid Use

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Massachusetts General HospitalNCT06201676

Observational

Optimization of Adaptive Rowing Seating (OARS)

Adaptive sports programs are integral components to combating Veteran isolation, promoting wellbeing and seeking to build teams, networks, communities. These a…

Spinal Cord DiseasesSpinal Cord InjuriesNeurodegenerative Disorders+1 more

Estimated

~$10 – $675

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT07099625