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26,914 recruiting studies available now

Colon Health Champion Program

This is a single arm-proof-of-concept trial. The primary goal of this trial is to assess the feasibility and acceptability of the Colon Health Champion Program

Colorectal CancerCRC

Estimated

~$10 – $6,250

Virginia Commonwealth UniversityNCT07796334

Phase 2

UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases: Avoidance of Eloquent White Matter and Hippocampal Regions

In this proposal, the investigators introduce advanced diffusion and volumetric imaging techniques along with innovative, automated image parcellation methods …

Brain Metastases, AdultNeurocognitive FunctionCancer

Estimated

~$10 – $7,500

Jona Hattangadi-GluthNCT04343157

Investigating the Mechanistic Biology of Primary Immunodeficiency Disorders

Background: Primary immunodeficiency disorders, or PIDs, are diseases that weaken the immune system. This makes it easier for a person to get sick. Some PIDs …

Primary Immunodeficiency Disorders

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT03394053

Phase 2

A Randomized Phase 2 Trial of ASTX727 +/- Iadademstat in Accelerated/Blast-Phase Philadelphia Chromosome-Negative Myeloproliferative Neoplasms (MPNs)

This phase II trial compares the effect of ASTX727 in combination with iadademstat to ASTX727 alone in treating patients with accelerated or blast phase Philad…

Accelerated Phase Myeloproliferative NeoplasmBlast Phase Myeloproliferative NeoplasmEssential Thrombocythemia+5 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT06661915

Phase 2

Prospective Randomized Phase II Study Evaluating Efficacy and Safety of IgPro20 as Infection Prophylaxis in Patients With Multiple Myeloma and Hypogammaglobulinemia Receiving Therapy With a Bispecific Monoclonal Antibody (BsAbs)

The main purpose of this study is to see if IgPro20 can prevent infection in people with multiple myeloma (MM) who have hypogammaglobulinemia from receiving bi…

Multiple MyelomaHypogammaglobulinemiaHypogammaglobulinemia, Acquired

Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT06976476

The Phenotype and Etiology of Proteus Syndrome

This study will examine rare congenital disorders that involve malformations and abnormal growth. It will focus on patients with Proteus syndrome, whose physic…

Proteus SyndromePIK3CA Related Overgrowth Spectrum

Estimated

~$10 – $675

National Human Genome Research Institute (NHGRI)NCT00001403

Phase 3

A Long-Term Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Multiple Maintenance Doses of Oral Once Daily Aleniglipron for Chronic Weight Management in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

This is randomized, double-blind, placebo-controlled study of the long-term efficacy, safety, and tolerability of multiple doses of aleniglipron in participant…

ObesityOverweightChronic Weight Management+1 more

Estimated

~$10 – $8,750

Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure TherapeuticsNCT07654374

Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

Background: Cancer has a major impact in the United States and across the world. In 2015, over 1.5 million new cases of cancer were diagnosed in the U.S. Rese…

Multiple MyelomaLymphoma, Non-HodgkinLeukemia-Lymphoma, Adult T-Cell+2 more

Estimated

~$10 – $675

National Cancer Institute (NCI)NCT02682667

Generation of Induced Pluripotent Stem (iPS) Cell Lines From Somatic Cells of Participants With Eye Diseases and From Somatic Cells of Matched Controls

Background: \- Best Vitelliform Dystrophy (Best disease), Late-Onset Retinal Degeneration (L-ORD), and Age-Related Macular Degeneration (AMD) all affect the r…

Retinal DiseaseAMDRetinal Degeneration+1 more

Estimated

~$10 – $675

National Eye Institute (NEI)NCT01432847

Observational

A Self-Help Intervention to Improve Functioning, Symptoms, and Treatment Utilization Among Non-Treatment Engaged Post 9/11 Veterans With Depression or PTSD Symptoms

It is important to provide support and resources for the many post-9/11 Veterans with mental health symptoms and poor psychosocial functioning who do not engag…

DepressionStress Disorders, Post-Traumatic

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT07202325

Phase 1

A Phase 1, Open-Label, Multi-Center, Safety and Efficacy Study of PRT12396 in Participants With Polycythemia Vera and Myelofibrosis

This is a first-in-human, open-label, multi-center Phase 1 study designed to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of P…

Polycythemia Vera (PV)Myelofibrosis (MF)Myeloproliferative Neoplasms (MPNs)+3 more

Estimated

~$10 – $8,750

Prelude TherapeuticsNCT07469891

Phase 1

A Phase 1/2, First-in-Human, Multi-Arm, Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Efficacy of VV-14303, an Adeno-associated Virus Vector-mediated Fibroblast Growth Factor 21 (FGF21) Gene Therapy, in Adults With Metabolic Dysfunction-associated Steatohepatitis (MASH)

A Study of VV-14303 for the Treatment of Metabolic dysfunction-associated steatohepatitis (MASH)

Metabolic Dysfunction-associated Steatohepatitis (MASH)

Estimated

~$10 – $8,750

Kriya Therapeutics, Inc.NCT07732400