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An Open-Label, Multicenter, Phase 1/1b Study of RNDO-564 as Monotherapy and in Combination With Pembrolizumab in Adult Participants With Relapsed/Refractory Locally Advanced or Metastatic Urothelial Cancer and Other Solid Tumors Associated With Nectin-4 Expression

The main goal of this study is to evaluate how safe and tolerable RNDO-564 is and to identify the best dose of RNDO-564 as a single agent and in combination wi…

Non Small Cell Lung CancerCervical CancerHead and Neck Squamous Cell Cancer+7 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Rondo TherapeuticsNCT07218003

Psychosocial Burden and Quality of Life in Caretakers of Hepatobiliary Cancer Patients: A Survey-Based Analysis

Assess caregiver psychosocial burden, including Quality of Life, health, interpersonal relationship, access to support, and explore associated sociodemographic…

Psychosocial Problem

Estimated

~$10 – $750

Actual pay is set by the research site.

Methodist Health SystemNCT07644091

Phase 1

Aging and Task-Specific Training to Reduce Falls

The goal of this clinical trial is to examine the effects of a novel task-specific balance training for reducing environmental falls in community ambulatory ol…

Fall Prevention

Estimated

~$500 – $7,500

Actual pay is set by the research site.

University of Illinois at ChicagoNCT07094659

Observational

Phosphatidylethanol and Other Ethanol Consumption Markers

This study is intended to help the investigators understand how a biomarker found in the blood may be used to better identify the quantity and different patter…

Healthy VolunteerAlcohol Consumption

Estimated

~$10 – $750

Actual pay is set by the research site.

The University of Texas Health Science Center at San AntonioNCT06747364

Observational

Health Behavior Intervention for Adults With Type 1 Diabetes

Type 1 diabetes (T1D) affects approximately 2 million Americans, and only 2 in 8 young adults ages 18-31 years achieve glycemic targets (glycated hemoglobin A1…

Type1diabetes

Estimated

~$10 – $750

Actual pay is set by the research site.

Emory UniversityNCT05823142

Phase 1

A Phase Ib Study of VK-2019 in Patients With Relapsed or Refractory EBV+ Diffuse Large B-cell Lymphomas (DLBCL)

This is a Phase Ib in adult patients with relapsed or refractory EBV-positive DLBCL using daily oral dosing of VK-2019 in three dose escalation cohorts: 600 mg…

Diffuse Large B Cell Lymphoma RefractoryDiffuse Large B Cell Lymphoma RelapsedEpstein-Barr Virus (EBV) Infection

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Pierluigi PorcuNCT06789159

Observational

Brain Organization, Development, and Response to Intervention in Individual Neonates

The goal of this study is to learn about brain connectivity and if massaging babies shortly after birth has an impact. Half of the recruited babies will receiv…

Development, Infant

Estimated

~$10 – $750

Actual pay is set by the research site.

Washington University School of MedicineNCT05843396

A Single-arm, Multicenter Prospective Study to Evaluate the Diagnostic Performance of PROSTest in Men With PSA ≥ 3ng/ml Using Biopsy as the Sole Ground Truth

This prospective observational study will enroll men referred for prostate biopsy due to elevated PSA and/or abnormal digital rectal examination, with or witho…

Prostate CancerUrologyProstate Cancer (Diagnosis)

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Wren Laboratories LLCNCT07454603

Phase 4

Musculoskeletal Resiliency and Adaptation to Sex Steroid Suppression and Replacement During Multi-Stressor Training

Non-combat-related muscle, tendon and bone injuries are the most common injuries suffered by military personnel, particularly in new recruits. These injuries i…

Musculoskeletal InjuryHypogonadismHormonal Contraception

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Bradley NindlNCT06455969

Phase 2

Window of Opportunity Assessment of [Fam-]Trastuzumab DERuxtecan-nxki (T-DXd) Brain Tumor Penetration and Efficacy (WOnDER-BT)

The purpose of this study is to find out how much tratuzumab deruxtecan (T-DXd) can penetrate the tumor when injected into the body, and whether T-DXd may be a…

Brain CancerGlioblastomaMetastatic Cancer+2 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT06058988

Phase 1

Prospective Study of Complication Rates in Cataract Surgery Patients Treated With Combined Pre-operative NSAID, OMIDRIA, and Subconjunctival Triamcinolone Acetonide Compared With Peri-operative Standard of Care

This is a multicenter, 2-arm, randomized, prospective study of patients slated for bilateral cataract extraction. One eye will be randomized to the Study Arm, …

Cataract

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Inder Paul Singh, M.D.NCT06681688

Phase 2

Functional Neuroimaging of the Enhanced Antidepressant Efficacy of Ketamine in a Biologically-Enriched Subgroup

A single subanesthetic dose infusion of the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine has rapid and robust antidepressant effects in patients wi…

Magnetic Resonance ImagingMajor DepressionAlcoholism

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Mark NiciuNCT02122562