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27,333 recruiting studies available now

A Phase II Basket Study of the Oral TRK Inhibitor Larotrectinib (BAY2757556) in Subjects With NTRK Amplification Positive and Pan-TRK Positive Tumors

This phase II trial studies the effect of larotrectinib in treating patients with NTRK gene amplification positive solid tumors that have spread to nearby tiss…

Locally Advanced Malignant Solid NeoplasmMetastatic Malignant Solid Neoplasm

Estimated

~$75 – $2,000

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT04879121

Observational

The Effect of Rinsing on Ocular Inflammation and Symptoms in Patients With Dry Eye Disease

The central hypothesis is that inflammation contributes to dry eye and that rinsing the palpebral conjunctiva, bulbar conjunctiva, and fornices will reduce the…

Dry Eye SyndromesDry EyeOcular Surface Disease

Estimated

~$10 – $1,125

Actual pay is set by the research site.

RinsadaNCT07618364

Observational

Structured Opportunities for Connection to Improve Aging-related Loneliness

The goal of this early phase clinical trial is to determine the impact of participation in planned social activities among adults 55 years of age or older, who…

Loneliness

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Endeavor HealthNCT07708844

Coagulopathy of Immunodermatologic Diseases The Molecular, Prognostic, and Therapeutic Implications of Crosstalk Between Coagulation, Fibrinolysis, and Inflammation in Immune-Mediated Skin Diseases

This study will examine the coagulation and fibrinolysis profiles of those with autoimmune skin diseases. Blood samples will be collected from participants wit…

Autoimmune Bullous Dermatosis

Estimated

~$10 – $750

Actual pay is set by the research site.

University of NebraskaNCT06037187

Phase 2

A Phase II Randomized, Decentralized, De-escalation Study in Patients With Metastatic Hormone-Sensitive Prostate Cancer Achieving Optimal PSA Response (OPTIMAS)

The purpose of this study is to evaluate intermittent relugolix + androgen receptor pathway inhibitor (ARPI) in patients with metastatic hormone-sensitive pros…

Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of UtahNCT07216248

Developing Digital Speech Biomarkers of Bulbar Disease Decline in Spanish-Speaking Persons With Amyotrophic Lateral Sclerosis

The goal of this observational study is to learn how speech and breathing change over time in Spanish-speaking individuals with amyotrophic lateral sclerosis (…

Amyotrophic Lateral SclerosisLou Gehrig's DiseaseALS

Estimated

~$10 – $750

Actual pay is set by the research site.

Nova Southeastern UniversityNCT07341334

Phase 3

A Phase III, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Once Weekly Petrelintide vs. Placebo in Participants With Overweight or Obesity

This study will evaluate the efficacy and safety of petrelintide compared with placebo, in conjunction with a reduced-calorie diet and increased physical activ…

Obesity or Overweight

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Hoffmann-La RocheNCT07843498

Phase 2

Phase 2, Open-label Evaluation of Olorofim in Early Coccidioidal Meningitis

This research study is being conducted to learn more about the use of olorofim in Coccidioidal (Cocci) meningitis, a rare but serious fungal infection that aff…

Coccidioidal Meningitis

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Fariba DonovanNCT07385638

Phase 2

A Phase 2, Open-Label, Dose Escalation Trial Assessing the Safety, Tolerability, and Treatment Effect of Belzupacap Sarotalocan (AU-011) With Suprachoroidal Administration in Subjects With Metastases to the Choroid

The primary objective is to assess the safety and tolerability of bel-sar treatment in subjects with metastases to the choroid from any primary solid tumor.

Eye CancerPrimary Cancer

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Aura BiosciencesNCT06643884

Phase 2

A Phase 2 Multicenter Study of the Combination Zanubrutinib, Bendamustine, and Rituximab in Previously Untreated Waldenström Macroglobulinemia (ZEBRA Trial)

The purpose of this study is to determine the very good partial response (VGPR) or better rate in participants with Waldenström macroglobulinemia (WM). The na…

Waldenstrom Macroglobulinemia

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Massachusetts General HospitalNCT06561347

Observational

Evaluation of the Tap Trust Intervention on Water Security Experiences and Beverage Intake

The primary aim of this clinical trial is to determine whether the Tap Trust intervention increases water intake among preschool-aged children and their parent…

Beverage IntakeChild Health and Nutrition

Estimated

~$10 – $750

Actual pay is set by the research site.

Stanford UniversityNCT07197216

A Prospective, Multi-center Observational Study Characterizing Clinical Outcomes of Patients Receiving Abrocitinib for Moderate-to-severe Atopic Dermatitis Who Had an Inadequate Response (or Intolerance) to ≤2 Previous Biologic Therapies Approved for Moderate-to-severe Atopic Dermatitis

This is a prospective, multi-center observational study characterizing clinical and patient reported outcomes of patients receiving abrocitinib for moderate-to…

Atopic DermatitisAtopic Dermatitis, UnspecifiedDermatitis, Atopic

Estimated

~$10 – $1,125

Actual pay is set by the research site.

PfizerNCT06899204