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A Modern Comparison of Suture Repair With Mesh Repair for Incisional Hernia

The goal of this randomized controlled trial is to compare the difference in quality of life at one year postoperatively for patients undergoing incisional her…

Incisional Hernia

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Clayton PetroNCT05599750

Observational

A Prospective, Randomized, Controlled, Multi-Center Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation

Prospective, randomized, controlled study to assess the safety and effectiveness of GalaFLEX LITE™ Scaffold in revision surgery for reduction of capsular contr…

Capsular Contracture Associated With Breast ImplantCapsular Contracture Grade IIICapsular Contracture Grade IV

Estimated

~$10 – $1,125

Actual pay is set by the research site.

C. R. BardNCT05945329

Phase 1

A Pilot Study to Evaluate Biomarkers and Safety of Dapagliflozin Concomitant With Neoadjuvant Therapy for Patient With HER2-negative Early-stage Breast Cancer and Hyperinsulinemia

The primary objective of the study is to assess metabolic plasma markers of insulin resistance in patients with early-stage HER2-negative breast cancers receiv…

Breast CancerHyperinsulinismHER2-negative Breast Cancer

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Yale UniversityNCT05989347

Observational

Part A: Effect of Prophylactic Vertebroplasty Combined With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

This clinical trial studies the side effects of stereotactic radiosurgery and how well it works with or without vertebroplasty, separation surgery, or immunoth…

Hematopoietic and Lymphoid Cell NeoplasmMalignant Solid NeoplasmMetastatic Malignant Neoplasm in the Spine

Estimated

~$10 – $750

Actual pay is set by the research site.

Ohio State University Comprehensive Cancer CenterNCT05178472

Phase 3

A Phase 3 Open-Label, Randomized Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUIN-CLL-314)

The purpose of Part 1 of this study is to compare the efficacy and safety of pirtobruitinib (LOXO-305) to ibrutinib in participants with CLL/SLL; participants …

Chronic Lymphocytic LeukemiaLeukemia, LymphocyticLeukemia, B-cell+1 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Loxo Oncology, Inc.NCT05254743

Observational

Single Arm Intervention Trial of DEKA TWIIST TM Insulin Pump Utilizing Tidepool Loop Algorithm in Pregnant People With Pre-existing Type 1 Diabetes

Suboptimal glycemic control during pregnancy contributes to adverse maternal and fetal health outcomes and previous automated insulin delivery (AID) studies ha…

Type 1 DiabetesPregnancy

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT07808385

Phase 1

A Phase 1, Randomized, Blinded, Placebo-Controlled, Single- and Multiple-Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB142 in Healthy Adults

In this study, researchers will learn more about the safety of BIIB142 and how it is processed in the body. This is the first time that researchers will learn …

Healthy Volunteer

Estimated

~$500 – $11,250

Actual pay is set by the research site.

BiogenNCT07133828

Observational

Safety and Efficacy of Low-Flow ECMO in a Multi-modal Cohort of Adults in Respiratory Failure

The current standard of care (SOC) for treatment of patients with acute respiratory distress syndrome (ARDS), inhalation injury, volume overload, and/or pulmon…

Acute Hypoxemic Respiratory FailureMechanical VentilationAcute Respiratory Distress Syndrome (ARDS)

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Institute for Extracorporeal Life SupportNCT06938217

Observational

The Benefits of Home Exercise in Pulmonary Hypertension Interstitial Lung Disease

This study evaluates the effects of a structured home exercise program in participants with pulmonary hypertension associated with interstitial lung disease. P…

Pulmonary HypertensionInterstitial Lung Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

University of RochesterNCT07561034

Comprehensive Molecular and Clinical Evaluation of Pediatric and Adult MDS

Background: Myelodysplastic syndromes (MDS) occur when the cells that make blood cells are abnormal. There are limited treatment options for MDS. Researchers …

Myelodysplastic Syndromes

Estimated

~$10 – $675

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT05350748

Phase 1

PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)

Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from COVID-19 have long-term symptoms that affect the brain. These include h…

Long COVIDPost Acute Sequelae of COVID-19

Estimated

~$500 – $6,750

Actual pay is set by the research site.

National Institute of Mental Health (NIMH)NCT06920628

Phase 2

A Phase 2 Trial of Single-Agent Pirtobrutinib for Elderly Patients With CLL

This phase II trial studies how well pirtobrutinib works in treating elderly patients with chronic lymphocytic leukemia (CLL). Bruton tyrosine kinase (BTK) inh…

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Jennifer WoyachNCT07685717