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26,899 recruiting studies available now

Communicating Health Options to Inform Care and Empower Strategic Care Planning (CHOICES): A Multi-layer Randomized Case Vignette Study.

To learn more about how the delivery of medical information affects therapy choices for participants with advanced forms of cancer.

Health OptionsStrategic Care Planning

Estimated

~$10 – $750

M.D. Anderson Cancer CenterNCT06722846

Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research Studies on Antiretroviral Naive HIV-1 Research Participants

There is evidence that early and aggressive treatment with antiretroviral drugs can prevent the loss of immune cell function that accompanies HIV infection. Th…

HIV

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT00039689

Phase 4

A Phase 3b/4, Interventional, Prospective, Multicenter, Open-Label Study Evaluating the Effectiveness of a Gradual Titration Regimen to Optimize CBD-OS as Add-On Therapy in Adults With Lennox-Gastaut Syndrome

This is a Phase 3b/Phase 4 study. The purpose of this study is to learn more about the efficacy of using CBD-OS as an add-on therapy for the treatment of LGS i…

Lennox-Gastaut Syndrome

Estimated

~$10 – $8,750

Jazz PharmaceuticalsNCT07728097

Phase 3

A Phase III, Multicentre, Randomised, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Elafibranor in Adult Participants With Primary Sclerosing Cholangitis

The purpose of this study is to find out how well and safely elafibranor works compared to placebo in adult participants with Primary sclerosing cholangitis (P…

Primary Sclerosing Cholangitis

A Phase 2 Study of Imatinib Therapeutic Drug Monitoring in Gastrointestinal Stromal Tumor

Imatinib can lead to long recurrence free survival in patients diagnosed with gastrointestinal stromal tumors (GIST); however side effects can significantly hi…

Gastrointestinal Stromal Tumors

Estimated

~$10 – $7,500

Reema A. PatelNCT05493215

Phase 1

Repurposing a Combination Antiretroviral Drug Therapy to Target Retrotransposons and Treat Early Alzheimer's Disease

The goal of this clinical trial is to determine the safety, tolerability, drug levels and biological effects of two doses of emtricitabine (FTC) and tenofovir …

Alzheimer's Disease

Estimated

~$10 – $6,250

Brigham and Women's HospitalNCT07795307

Phase 3

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Nalbuphine Extended-Release Tablets for the Treatment of Chronic Cough in Participants With Idiopathic Pulmonary Fibrosis

The primary purpose is to evaluate the safety and efficacy of NAL ER for the treatment of chronic cough in participants with Idiopathic Pulmonary Fibrosis (IPF…

Idiopathic Pulmonary Fibrosis

Estimated

~$10 – $8,750

Trevi TherapeuticsNCT07671911

Phase 1

A Phase I Study of the Intrathecal Administration of Resiniferatoxin for Treating Severe Refractory Pain Associated With Advanced Cancer

This study will examine the safety of giving the experimental drug, resiniferatoxin (RTX), to treat severe pain in patients with advanced cancer. RTX is a chem…

Intractable PainPalliative Care

Estimated

~$10 – $5,625

National Institute of Dental and Craniofacial Research (NIDCR)NCT00804154

Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach

Background: Primary sclerosing cholangitis is a rare chronic liver disease. It affects the bile ducts of the liver. It can result in bile duct infections, ci…

Primary Sclerosing Cholangitis

Estimated

~$10 – $675

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT04685200

Phase 3

An Open-label Long-term Follow-up Study to Evaluate the Effects of Sotatercept When Added to Background Pulmonary Arterial Hypertension (PAH) Therapy for the Treatment of PAH (MK-7962-038)

Researchers are looking for more ways to treat PAH. In PAH, the blood vessels in the lungs become thick and narrow, which makes it harder for blood to flow. Th…

Pulmonary Arterial Hypertension

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT07218029

Phase 2

Phase 2 Trial of Obinutuzumab and CC-99282 for Patients With Previously Untreated High Tumor Burden Follicular Lymphoma

To learn if obinutuzumab in combination with CC-99282 can help to control previously untreated, high tumor burden FL

Follicular LymphomaTumor

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT06108232

Phase 1

A Phase I Study Evaluating Allogeneic Memory T Cells Engineered to Express Chimeric Antigen Receptors Specific for CD19 for the Treatment of Pediatric and Young Adult Patients ≤ 21 Years of Age With Relapsed or Refractory CD19-Positive Leukemia

This is a Phase I clinical study evaluating the safety and maximum tolerated dose of a novel CAR T-cell product: allogeneic memory (CD45RA- negative) T-cells e…

Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia, RefractoryPediatric ALL

Estimated

~$10 – $6,250

St. Jude Children's Research HospitalNCT04881240