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27,370 recruiting studies available now

Supplemental Oxygen in Pulmonary Embolism (SO-PE)

A study of how supplemental oxygen helps patients with acute pulmonary embolism (PE). Hypothesis: Oxygen affects right ventricular dysfunction (RVD) in patien…

Pulmonary EmbolismVenous ThromboembolismMetabolomics+1 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Massachusetts General HospitalNCT05891886

Collection of Whole Blood Specimens From Pregnant Women at Increased Risk of Fetal Chromosomal Abnormality for Use in Development of a Noninvasive Prenatal Test in the Detection of the Relative Quantity of Chromosomal Material in Circulating Cell-Free DNA Extracted From Maternal Plasma

The specimen collection is designed for the purpose of the development of a noninvasive prenatal test for T21.

Down SyndromeFetal Aneuploidy

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Sequenom, Inc.NCT01429389

Phase 1

A Phase 1b, Multicenter, Dose Escalation, Evaluation of Safety and Tolerability of ASP7317 for Geographic Atrophy Secondary to Age-related Macular Degeneration

Age-related macular degeneration (AMD) is an eye disease which causes people to lose their sharp central vision over time. Aging damages the macula, which is i…

Age-Related Macular Degeneration

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Astellas Institute for Regenerative MedicineNCT03178149

A Retrospective and Prospective Natural History of Genetic Vasculopathies

This study will combine retrospective review of medical records from patients with ACTA2 and ongoing collection of clinical data using standardized instruments…

Multisystemic Smooth Muscle Dysfunction SyndromeACTA2

Estimated

~$10 – $750

Actual pay is set by the research site.

Massachusetts General HospitalNCT06552052

Phase 1

WOPPPR: Window of Opportunity Phase I and Phase II Trial Combining PD-1 Inhibition and Neoadjuvant Proton or Photon Radiation Therapy in Recurrent Head and Neck Squamous Cell Carcinoma

The purpose of the Phase I study is to see if it is safe to use X-ray photon radiation (XRT) and proton radiation (PT) before surgery in patients with recurren…

Head and Neck CancerRecurrent Head and Neck Squamous Cell Carcinoma

Estimated

~$150 – $2,700

Actual pay is set by the research site.

University of CincinnatiNCT07213934

Observational

Focus of Attention Effect on Sit to Stand Symmetry in Individuals Post Chronic Stroke: A Randomized Cross-over Trial

The purpose of this study is to fill some gaps in the literature by examining the effects of focus of attention on motor learning and motor performance of sit …

Stroke

Estimated

~$10 – $750

Actual pay is set by the research site.

Western Carolina UniversityNCT07460804

Phase 2

Topical Application of Tranexamic Acid (CYKLOKAPRON®) to Reduce Blood Loss During Spine Surgery

This study is designed to evaluate the efficacy of topical tranexamic acid to reduce perioperative blood loss, reduction in postoperative drain output and allo…

Spinal InjuriesSpinal Deformity

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Columbia UniversityNCT02314988

Phase 4

Impact of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02%/Latanoprost 0.005% to Treat Glaucoma

To evaluate the effect of brimonidine tartrate 0.025% on conjunctival hyperemia in patients treated with netarsudil 0.02%/latanoprost 0.005% mono-therapy for i…

Glaucoma

Estimated

~$25 – $1,400

Actual pay is set by the research site.

Insight Eyecare Specialties, Inc. dba Vision Source Eyecare,NCT07209410

Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease

The Montalcino Aortic Consortium (MAC) will provide the infrastructure to assemble large cohorts of patients with mutations in known heritable thoracic aortic …

Aortic AneurysmAortic DissectionAortic Diseases

Estimated

~$10 – $750

Actual pay is set by the research site.

The University of Texas Health Science Center, HoustonNCT04005976

Pharmacogenomic-Based Medication Safety Reviews of Persons With Intellectual and Developmental Disabilities

The purpose of this study is to assess the feasibility of a comprehensive medication review and PGx initiative as part of the care process for individuals in t…

Intellectual Disability, MildIntellectual Disability, Mild to ModerateDevelopmental Disability

Estimated

~$10 – $1,050

Actual pay is set by the research site.

GalenusRx, Inc.NCT07092852

Observational

Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis

Differentiating between septic arthritis and other causes of joint inflammation in pediatric patients is challenging and of the utmost importance because septi…

Joint InfectionInfection of Hip Joint (Disorder)Infection of Shoulder Joint+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Hospital for Special Surgery, New YorkNCT03704766

Observational

PRISM-NLM: Prostatectomy Intraoperative Surgical Margin Assessment With Non-linear Microscopy

This study will evaluate the use of intraoperative nonlinear microscopy (NLM) for surgical margin assessment during nerve-sparing radical prostatectomy in part…

Prostate Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

Beth Israel Deaconess Medical CenterNCT07516808