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A Phase 1A/1B, Multicenter, Nonrandomized, Open-Label, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of YL201 as a Single Agent and in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors

This is a phase 1, multicenter, nonrandomized, open-label, first-in-human study of YL201 conducted in China and the United States. The study will include 2 par…

Advanced Solid Tumor

Estimated

~$150 – $4,200

Actual pay is set by the research site.

MediLink Therapeutics (Suzhou) Co., Ltd.NCT05434234

Phase 1

Xylitol Use for Decolonization of C. Difficile in Patients With Inflammatory Bowel Disease

This is a randomized, placebo-controlled, dose-ranging study to assess the safety and efficacy of xylitol as an oral therapeutic for decolonization of C. diffi…

Inflammatory Bowel DiseasesClostridioides Difficile Infection

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Brigham and Women's HospitalNCT05852587

Enhancing Resilience Among Patients With Stroke: Implementation of High Intensity Home-based Rehabilitation

The goal of this observational study is to test whether a model of high-intensity home-based rehabilitation (HIHR) helps patients get good outcomes after treat…

StrokeStroke Rehabilitation

Estimated

~$10 – $750

Actual pay is set by the research site.

Duke UniversityNCT07098286

Investigation of Smoldering Inflammation in Multiple Sclerosis

The goal of this observational study is to learn about inflammation in those with relapsing remitting Multiple Sclerosis (MS). The main questions it aims to an…

Multiple Sclerosis

Estimated

~$10 – $750

Actual pay is set by the research site.

Washington University School of MedicineNCT06591429

Viability Assessment Using Flavin Mononucleotide (FMN) Measured in Perfusate and Bile During Normothermic Machine Perfusion: an International, Multi-center Validation Study

Discarded perfusate samples will be collected from donors after circulatory death (DCD) or donors after brain death (DBD) organs during the machine perfusion p…

Liver Transplant Disorder

Estimated

~$10 – $750

Actual pay is set by the research site.

The Cleveland ClinicNCT07315204

Observational

Pediatric Scoliosis Surgery: Enhanced Recovery With Erector Spinae Plane Blockade Utilizing Surgically Placed Catheters

Providing effective analgesia after spinal fusion for idiopathic scoliosis remains a challenge with significant practice variation existing among high volume s…

Scoliosis; JuvenileScoliosis; Adolescence

Estimated

~$10 – $750

Actual pay is set by the research site.

Stanford UniversityNCT04153994

PRISM: PRecision Integrated Saturation Monitor A Novel Approach to Monitoring Oxygen Saturation in Children A Prospective, Observational, Comparative Validation Clinical Study to Evaluate the Accuracy of a Novel Abdominal Pulse Oximeter With Integrated Motion Detection and Skin Tone Calibration Against Arterial Blood Gas (SaO₂) Measurements and Conventional Fingertip Pulse Oximetry (SpO₂) in Pediatric Patients.

The purpose of this study is to find out if an abdominal pulse oximeter device is as accurate as a conventional fingertip pulse oximeter in pediatric patients.…

CHD - Congenital Heart DiseaseSingle Ventricle Heart Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

Le Bonheur Children's HospitalNCT07686341

Phase 1

A Phase 1 Study of 5-Fluorouracil in Combination With Abemaciclib in Metastatic, Refractory CRC

This phase I trial tests the safety, side effects, and best dose of abemaciclib in combination with 5-fluorouracil and how well it works in treating patients w…

Metastatic Microsatellite Stable Colorectal CarcinomaRefractory Microsatellite Stable Colorectal CarcinomaStage IV Colorectal Cancer AJCC v8

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06654037

Observational

Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention

The investigators will conduct a Type I hybrid effectiveness-implementation study to test an integrated telehealth intervention among 400 overweight and obese …

Chronic Obstructive Pulmonary DiseaseObstructive Sleep ApneaOverweight and Obesity

Estimated

~$10 – $750

Actual pay is set by the research site.

Seattle Institute for Biomedical and Clinical ResearchNCT06390345

Phase 1

Phase Ib Study to Assess the Efficacy and Safety of Epcoritamab in Relapsed or Refractory Post-Transplant Lymphoproliferative Disorder

This phase Ib trial tests the safety and effectiveness of epcoritamab in treating patients with post-transplant lymphoproliferative disorder (PTLD) that has co…

Diffuse Large B-Cell Lymphoma Post-Transplant Lymphoproliferative DisorderEBV-Related Post-Transplant Lymphoproliferative DisorderRecurrent Monomorphic Post-Transplant Lymphoproliferative Disorder+3 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Phase 3

Phase 3, Double-blind, Placebo-controlled, Multicentre Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

The primary objective of this study is to evaluate the efficacy of two different doses of Atenativ, versus placebo, in restoring and maintaining heparin respon…

Acquired Antithrombin Deficiency

Estimated

~$50 – $2,100

Actual pay is set by the research site.

OctapharmaNCT06096116

Observational

A Pilot of Memory Support System for Older Chinese Americans With Mild Cognitive Impairment

The Memory Support System (MSS) from the Healthy Action to Benefit Independence \& Thinking® (HABIT) Program is an evidence-based, non-pharmacological interven…

Mild Cognitive Impairment (MCI)

Estimated

~$10 – $750

Actual pay is set by the research site.

Icahn School of Medicine at Mount SinaiNCT07142499