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Intrathecal Administration of MELPIDA (AAV9/AP4M1) For Hereditary Spastic Paraplegia Type 50 (SPG50): A Phase 3, Open-Label Trial With Matched Prospective Concurrent Control Arm

Phase 3, open-label study to assess the efficacy and safety of a single lumbar intrathecal administration of MELPIDA in individuals with Hereditary Spastic Par…

Hereditary Spastic Paraplegia Type 50

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Elpida Therapeutics SPCNCT06692712

Phase 2

Open-label Single-arm Phase 2 Trial of Trastuzumab Deruxtecan in Previously Treated HER2-Immunohistochemistry (IHC) 0 Advanced Breast Cancer

The purpose of this study is to test the good and bad effects of a drug called trastuzumab deruxtecan (T-DXd) in adult patients with metastatic HER2-negative b…

Breast Cancer Metastatic

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Yale UniversityNCT06750484

Phase 2

A Pilot Randomized Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)

Amyotrophic lateral sclerosis (ALS) is a disease that causes weakness of the muscles of the body. The disease can eventually lead to severe breathing problems,…

Amyotrophic Lateral Sclerosis (ALS)Chronic Respiratory FailureNeuromuscular Disease Patients+7 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of PennsylvaniaNCT07071935

Observational

Baby Steps to Care - Improving Access to Prenatal Care From the Emergency Department

The purpose of this research study is to understand if receipt of extra prenatal resources from the ED visit improves i) the patient's ability to engage in pre…

Prenatal Follow Up Care

Estimated

~$10 – $750

Actual pay is set by the research site.

University Hospitals Cleveland Medical CenterNCT07499648

Exhaled Breath: A Novel Technique for Rapid Diagnosis of Respiratory Diseases and Infections

This study aims to use mass spectrometry techniques to analyze exhaled patient breath in non-COVID ICU-admitted patients requiring ventilation for a rapid and …

Pulmonary DiseaseCritical Illness

Estimated

~$10 – $750

Actual pay is set by the research site.

Oregon Health and Science UniversityNCT06775106

Observational

Non-Invasive Respiratory Monitor

This study will clinically evaluate a newly developed respiratory monitor - pneuRIP. The pneuRIP uses Respiratory Inductance Plethysmography (RIP) bands to mea…

Neuromuscular DiseasesHealthy Volunteers

Estimated

~$10 – $750

Actual pay is set by the research site.

Nemours Children's ClinicNCT02851043

Effect of Occupational Exposures on Cancer Pathophysiology Among Firefighters

This study aims to understand the effect of occupational exposures, including PFAS exposures, among firefighters.

Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

Vincere Cancer CenterNCT06173843

Phase 1

Hyperpolarized 13-C Pyruvate MRI Surveillance of Multiple Cancers

Many human diseases are characterized by their ability to alter existing metabolic pathways and interrupt cellular processes. Cancer exploits the Warburg effec…

ImageWarburg EffectTumors

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of Maryland, BaltimoreNCT05697406

Observational Study of the Safety of Intravenous Artesunate Treatment of Pregnant Women and Their Infants

This study is a prospective observational study in which a female patient who received IV Artesunate while pregnant can volunteer to provide information about …

PregnancyMalaria

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Amivas Inc.NCT05285735

Characterization of Monogenic Kidney Stone Diseases

This study will attempt to identify the specific gene (coded in the DNA) and changes (mutations) within that gene that are the cause of monogenic kidney stone …

Rare Kidney Stone Diseases

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT03305835

Phase 2

Phase II, Open-Labeled, Single-Armed Combination Treatment With Anastrozole, Fulvestrant and Abemaciclib for Hormone Receptor Positive, HER2(-) Metastatic Breast Cancer

This is a phase 2, open-label, singled-arm clinical trial determining efficacy of combination therapy with anastrozole, fulvestrant and abemaciclib in subjects…

Breast CancerMetastatic Breast CancerHormone Receptor-positive Breast Cancer+1 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of California, IrvineNCT05524584

TEMPUS GEMINI NSCLC STUDY: A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Non-Small Cell Lung Cancer (NSCLC)

GEMINI NSCLC Study is a non-interventional study that will be collecting clinical and molecular health information from patients with NSCLC who will receive lo…

Non-Small Cell Lung Cancer

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Tempus AINCT05236114