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A Multinational, Long-Term, Safety and Tolerability, Open-Label Extension Study of Subjects Who Have Participated in Avalyn Pharma Studies of Inhaled Antifibrotic Agents (AP-LTE-008 [SAIL])

This is an open-label extension study for participants who were previously enrolled in and completed an Avalyn Pharma Sponsored study with an inhaled antifibro…

Progressive Pulmonary FibrosisIdiopathic Pulmonary Fibrosis (IPF)

Estimated

~$10 – $8,750

Avalyn Pharma Inc.NCT06951217

Phase 1

A Phase 1 Study to Evaluate the Safety of KLN-1010, a Novel, In Vivo Gene Therapy to Generate Anti-B Cell Maturation Antigen (Anti-BCMA) Chimeric Antigen Receptor-T Cells (CAR-T) in Patients With Relapsed and Refractory Multiple Myeloma

The goal of this clinical trial is to evaluate the safety, tolerability, and recommended Phase 2 Dose (RP2D) of KLN-1010 in patients with relapsed or refractor…

Multiple Myeloma in RelapseMyeloma MultipleMultiple Myeloma Progression+11 more

Estimated

~$10 – $8,750

Kelonia Therapeutics, Inc.NCT07075185

Phase 1

A Phase 1/2 Study to Evaluate the Safety and Efficacy of Patritumab Deruxtecan in Gastrointestinal Cancers

Researchers want to learn if patritumab deruxtecan (MK-1022) can treat certain gastrointestinal (GI) cancers. The GI cancers being studied are advanced (the ca…

Gastrointestinal Cancer

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT06596694

Observational

The ReMATCH Study is a Prospective, Single Arm, Open Label, Multi-center, Study Utilizing the FARAPULSE PFA System, Including the FARAWAVE and FARAPOINT PFA Catheters

The ReMATCH Study is a prospective, single arm, open label, multi-center, study utilizing the FARAPULSE PFA System, including the FARAWAVE and FARAPOINT PFA Ca…

Persistent Atrial Fibrillation

Estimated

~$10 – $8,750

Boston Scientific CorporationNCT06735534

The Pathogenesis and Natural History of Sjogren's Disease

Background: -Sjogren s Disease (formerly: Sjogrens Syndrome, Sj(SqrRoot)(Delta)gren s syndrome) is a disease that affects about 1-4 million Americans. It is m…

Sjogren's SyndromeSalivary GlandPathogenesis

Estimated

~$10 – $675

National Institute of Dental and Craniofacial Research (NIDCR)NCT01425892

Phase 2

A Phase 2/3 Randomized, Placebo-Controlled, Double-blind, Clinical Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Systemic Left Ventricular Systolic Dysfunction (VALOR)

This study aims to compare the efficacy of vericiguat versus placebo on change in n-terminal pro-brain natriuretic peptide (NTproBNP) from baseline to Week 16 …

Heart FailureLeft Ventricular Systolic Dysfunction

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT05714085

Phase 2

A Phase 2, Open-Label, Parallel Cohort Study of Subcutaneous Amivantamab in Multiple Regimens in Patients With Advanced or Metastatic Solid Tumors Including EGFR-mutated Non-Small Cell Lung Cancer

The purpose of this study is to assess the anti-tumor activity and safety of amivantamab which will be administered as a co-formulation with recombinant human …

Carcinoma, Non-small-Cell Lung

Estimated

~$10 – $8,750

Janssen Research & Development, LLCNCT05498428

Phase 2

A Clinical Trial of Resistant Potato Starch for Gut MDRO Decolonization

Multidrug-resistant organisms (MDROs) cause serious infections that are difficult to treat, leading to increased morbidity and mortality, longer hospital stays…

Clostridium InfectionsMethicillin-resistant Staphylococcus Aureus (MRSA)Vancomycin-Resistant Enterococci+2 more

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT07792915

Phase 3

A Multicenter, Double-blind, Randomized, Placebo-controlled Study to Evaluate Efficacy and Safety of Seltorexant as Monotherapy in Adult and Elderly Participants With Major Depressive Disorder (MDD) and an Open-label Long-term Extension Treatment With Seltorexant

The main purpose of this study is to assess how well the study drug (JNJ-42847922) works (efficacy) compared with placebo in improving depressive symptoms in p…

Depressive Disorder, Major

Estimated

~$10 – $8,750

Janssen Research & Development, LLCNCT07573176

A Non-interventional Study of HLA-DRB1*04:01 Distribution in Adults With Recently Diagnosed Type 1 Diabetes (T1D)

This is a study to evaluate the HLA-DRB1\*04:01 genotype in adults that have been diagnosed with type 1 diabetes

Diabetes Mellitus, Type I

Estimated

~$10 – $1,050

GentiBio, IncNCT06860516

Phase 3

A Phase 3 Randomized, Double-blind, Placebo-controlled Study of Pasritamig (JNJ-78278343), a T Cell Engaging Agent Targeting Human Kallikrein 2, With or Without JNJ-87189401, a PSMA-CD28 Costimulatory Agent, Plus Best Supportive Care Versus Best Supportive Care for Late-line Metastatic Castration-resistant Prostate Cancer

The purpose of this study is to evaluate the overall survival (length of time from the start of study to date of death from any cause) for pasritamig (JNJ-7827…

Metastatic Castration-resistant Prostatic Neoplasms

Estimated

~$10 – $8,750

Janssen Research & Development, LLCNCT07164443

Phase 1

A Phase 1b/2, Open-Label Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

The purpose of this study is to assess the anti-tumor activity of amivantamab as a monotherapy (Cohorts A, B, and C), to assess the recommended phase 2 combina…

Advanced or Metastatic Colorectal Cancer

Estimated

~$10 – $8,750

Janssen Research & Development, LLCNCT05379595