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25,415 recruiting studies available now

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Background: High-grade neuroendocrine carcinomas (HGNEC) are cancers that develop in different parts of the body, including the digestive tract, genitals, nec…

Carcinoma, NeuroendocrineTumor, NeuroendocrineTumors, Neuroendocrine+2 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06406465

Phase 3

A Phase 3, Randomized, Placebo-Controlled Study of Adjuvant Intismeran Autogene Plus Subcutaneous Pembrolizumab and Berahyaluronidase Alfa (MK-3475A) or Intismeran Autogene Monotherapy Versus Placebo in Participants With Completely Resected High-Risk Stage I Non-Small Cell Lung Cancer (INTerpath-014)

Researchers are looking for new ways to treat high-risk, localized non-small cell lung cancer (NSCLC) that has been removed with surgery. People with high-ris…

Non-small Cell Lung Cancer

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT07513376

Phase 3

A Phase III Trial to Evaluate the Efficacy of the Addition of Inotuzumab Ozogamicin (a Conjugated Anti-CD22 Monoclonal Antibody) to Frontline Therapy in Young Adults (Ages 18-39 Years) With Newly Diagnosed Precursor B-Cell ALL

This phase III trial studies the side effects of inotuzumab ozogamicin and how well it works when given with frontline chemotherapy in treating patients with n…

B Acute Lymphoblastic Leukemia

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Alliance for Clinical Trials in OncologyNCT03150693

Phase 3

A Phase 3b, Multicenter, Two Stage, Double-blind, Long Term Follow up and Open Label Extension Study of Participants Who Have Completed the CBL-0301 or CBL-0302 Study for Reducing Abdominal Subcutaneous Fat (Stage 1)

A Phase 3b, Multicenter, Two stage, Double-blind, Long term Follow up and Open-label Extension Study of Participants Who have Completed the CBL-0301 or CBL-030…

Subcutaneous Fat

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Caliway Biopharmaceuticals Co., Ltd.NCT07733947

Phase 1

A Dose-Finding Study of Methadone Loading Dose Initiation for Opioid Use Disorder With Fentanyl Use

Methadone is an effective treatment for opioid use disorder (OUD), but starting it has become harder now that most people with OUD use fentanyl. Methadone is u…

Opioid Use Disorder (OUD)

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Ashish P Thakrar, MD MSNCT06877858

Intraoperative OCT Guidance of Intraocular Surger

The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging d…

Macular HolesEpiretinal MembraneDiabetic Retinopathy+7 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Duke UniversityNCT03713268

Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and Metabolism: A Natural History Study

Background: Many people in the United States are overweight or obese. This natural history study will look into how life events during childhood can impact ea…

Healthy VolunteerObestity

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT06690294

Phase 3

An Open-Label, Randomized, Controlled, Global Phase 3 Study Comparing Telisotuzumab Adizutecan (ABBV-400) Plus Bevacizumab to LONSURF (Trifluridine and Tipiracil) Plus Bevacizumab in Subjects With Refractory Metastatic Colorectal Cancer

Colorectal cancer (CRC) is the third most common type of cancer diagnosed worldwide. The purpose of this study is to assess the adverse events and change in di…

Colorectal Cancer

Estimated

~$50 – $2,250

Actual pay is set by the research site.

AbbVieNCT07525206

Phase 2

Phase II Trial of SMO/ AKT/ NF2/CDK Inhibitors in Progressive Meningiomas With SMO/ AKT/ NF2/CDK Pathway Mutations

This phase II trial studies how well vismodegib, focal adhesion kinase (FAK) inhibitor GSK2256098, and capivasertib work in treating patients with meningioma t…

Intracranial MeningiomaRecurrent MeningiomaNF2 Gene Mutation

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Alliance for Clinical Trials in OncologyNCT02523014

Observational

A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners

The purpose of this study is to evaluate the efficacy of an adaptive web intervention (Partners Connect) on military spouse drinking behaviors (CPs) and servic…

Alcohol AbuseAlcohol Use DisorderAlcohol Drinking+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Stanford UniversityNCT05619185

Phase 1

Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Phase 1, Double-Blind, Randomized, Placebo-Controlled, Dose Escalation Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies.

Background: People who have lung transplants often survive 6 or 7 years. But some people develop donor-specific antibodies (DSA) after their transplants; anti…

Lung Transplantation

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT06948097

Phase 1

A Platform Study of RAS(ON) Inhibitors in Patients With RAS-Mutated Non-Small Cell Lung Cancer (NSCLC)

The purpose of this platform study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of novel RAS(ON) inhibito…

Non-Small Cell Lung Cancer, NSCLCKRAS, NRAS, HRAS-mutated NSCLCKRAS G12C-mutated Solid Tumors, Lung Cancer+2 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Revolution Medicines, Inc.NCT06162221