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Prospective Registry-Based Study Evaluating the Effectiveness and Safety of Odevixibat in Participants With Alagille Syndrome (ALGS)

This study will collect information from patients with Alagille syndrome (ALGS) as they use odevixibat (Bylvay) in their daily lives. Odevixibat is a medicine…

Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Idiopathic CD4 lymphocytopenia (ICL) is a rare syndrome defined by consistently low CD4 T cell counts (\<300/mm\^3) without evidence of HIV infection or other …

Idiopathic CD4-PositiveT-Lymphocytopenia

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT02015013

Communicating Health Options to Inform Care and Empower Strategic Care Planning (CHOICES): A Multi-layer Randomized Case Vignette Study.

To learn more about how the delivery of medical information affects therapy choices for participants with advanced forms of cancer.

Health OptionsStrategic Care Planning

Estimated

~$10 – $750

M.D. Anderson Cancer CenterNCT06722846

Phase 4

A Phase 3b/4, Interventional, Prospective, Multicenter, Open-Label Study Evaluating the Effectiveness of a Gradual Titration Regimen to Optimize CBD-OS as Add-On Therapy in Adults With Lennox-Gastaut Syndrome

This is a Phase 3b/Phase 4 study. The purpose of this study is to learn more about the efficacy of using CBD-OS as an add-on therapy for the treatment of LGS i…

Lennox-Gastaut Syndrome

Estimated

~$10 – $8,750

Jazz PharmaceuticalsNCT07728097

Phase 3

A Phase III, Multicentre, Randomised, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Elafibranor in Adult Participants With Primary Sclerosing Cholangitis

The purpose of this study is to find out how well and safely elafibranor works compared to placebo in adult participants with Primary sclerosing cholangitis (P…

Primary Sclerosing Cholangitis

A Phase 2 Study of Imatinib Therapeutic Drug Monitoring in Gastrointestinal Stromal Tumor

Imatinib can lead to long recurrence free survival in patients diagnosed with gastrointestinal stromal tumors (GIST); however side effects can significantly hi…

Gastrointestinal Stromal Tumors

Estimated

~$10 – $7,500

Reema A. PatelNCT05493215

Phase 1

Repurposing a Combination Antiretroviral Drug Therapy to Target Retrotransposons and Treat Early Alzheimer's Disease

The goal of this clinical trial is to determine the safety, tolerability, drug levels and biological effects of two doses of emtricitabine (FTC) and tenofovir …

Alzheimer's Disease

Estimated

~$10 – $6,250

Brigham and Women's HospitalNCT07795307

Phase 1

A Phase I Study of the Intrathecal Administration of Resiniferatoxin for Treating Severe Refractory Pain Associated With Advanced Cancer

This study will examine the safety of giving the experimental drug, resiniferatoxin (RTX), to treat severe pain in patients with advanced cancer. RTX is a chem…

Intractable PainPalliative Care

Estimated

~$10 – $5,625

National Institute of Dental and Craniofacial Research (NIDCR)NCT00804154

Phase 2

Phase 2 Trial of Obinutuzumab and CC-99282 for Patients With Previously Untreated High Tumor Burden Follicular Lymphoma

To learn if obinutuzumab in combination with CC-99282 can help to control previously untreated, high tumor burden FL

Follicular LymphomaTumor

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT06108232

Phase 1

A Phase I Study Evaluating Allogeneic Memory T Cells Engineered to Express Chimeric Antigen Receptors Specific for CD19 for the Treatment of Pediatric and Young Adult Patients ≤ 21 Years of Age With Relapsed or Refractory CD19-Positive Leukemia

This is a Phase I clinical study evaluating the safety and maximum tolerated dose of a novel CAR T-cell product: allogeneic memory (CD45RA- negative) T-cells e…

Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia, RefractoryPediatric ALL

Estimated

~$10 – $6,250

St. Jude Children's Research HospitalNCT04881240

Phase 3

Triptorelin and Protection of Ovarian Reserve in Adolescents and Young Adults With Cancer

This phase III trial compares the effect of giving triptorelin vs no triptorelin in preventing ovarian damage in adolescents and young adults (AYAs) with cance…

Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm

Estimated

~$10 – $7,500

Children's Oncology GroupNCT06513962

Observational

Activities to Change Your Mood: A Test of the Acceptability and Initial Efficacy in Clinical Samples and Healthy Controls

This is a study investigating how brief online activities can influence mood and attitudes.

Schizophrenia Disorders

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT06911723