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27,069 recruiting studies available now

A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study Evaluating the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Subjects With α- or β-Non-Transfusion-Dependent Thalassemia

The primary objective of this study is to compare the effect of mitapivat versus placebo on anemia in pediatric participants with alpha- or beta-non-transfusio…

Non-Transfusion-dependent Alpha-ThalassemiaNon-Transfusion-dependent Beta-Thalassemia

Estimated

~$10 – $8,750

Agios Pharmaceuticals, Inc.NCT07517133

Integrating Molecular Pathology, Radiology, and Genetics to Improve Breast Cancer Risk

The purpose of this research is to better understand how benign breast diseases might lead to breast cancer, focusing on genetic factors and including a divers…

Breast Carcinoma

Estimated

~$10 – $750

Mayo ClinicNCT07207564

Phase 1

A Phase 1 Evaluation of the Safety of Belimumab in People With Idiopathic CD4 Lymphopenia and Autoantibodies (Phoebe)

Background: People with Idiopathic CD4 lymphopenia (ICL) have lower numbers of a type of white blood cell called CD4 cells. White blood cells fight against in…

Idiopathic CD4 Lymphopenia

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT04097561

Observational

Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate Cancer

Background: Active surveillance (AS) is a standard approach to treat low and intermediate risk prostate cancer. For AS, disease progression is monitored. AS u…

Prostate Cancer

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT04692675

Phase 4

A Clinical Study to Evaluate the Interstitial Dermal Fluid, Efficacy and Sun Protection Factor (SPF) of Two Test Materials According to an Adaptation of the Guidelines of the FDA Over-the-Counter Monograph M020: Sunscreen Drug Products for Over-the-Counter Human Use

Approximately 70 subjects (35 subjects per light and dark group) will be enrolled in this clinical study (to complete with a minimum of 10 subjects per skin ty…

EpidermisUltraviolet Exposure

Estimated

~$10 – $8,750

Good Molecules, LLCNCT07789639

Observational

The Impact of a Race-Based Stress Reduction Intervention on Well-Being, Inflammation, and DNA Methylation in African American Women at Risk for Cardiometabolic Disease

The goal of this clinical trial is to learn whether a stress reduction program called Resilience, Stress, and Ethnicity (RiSE) improves well-being, inflammatio…

RacismStressInflammation

Estimated

~$10 – $6,250

Loyola UniversityNCT05902741

Clinical and Immunologic Monitoring of Patients With Known or Suspected HIV Infection

This study will investigate HIV infection and associated conditions by monitoring infected patients. The study will also serve as a means for recruiting HIV-in…

HIV

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT00789009

Clinical & Genetic Studies in ALS and Other Neurodegenerative Motor Neuron Disorders

The purpose of this study is to collect, from patients with sporadic and familial ALS and their family members, clinical data and blood samples for extraction …

Amyotrophic Lateral Sclerosis

Estimated

~$10 – $750

Mayo ClinicNCT05474235

Phase 1

An Open-Label, Repeated-Dose Assessment of Zilucoplan Concentration in Breast Milk of Healthy Lactating Women

The purpose of this study is to assess the steady state (SS) concentrations of zilucoplan (ZLP) and its major metabolites in mature breast milk of healthy stud…

Healthy Participants

Estimated

~$10 – $8,750

UCB Biopharma SRLNCT06961747

Observational

Research to Foster an Opioid Use Disorder Treatment System Patients Can Count On: Project 2 - Producing Outcome Measures for OTP Quality Improvement

This study tests ways to help opioid treatment programs (OTPs) keep patients in care. Staying on methadone or buprenorphine is linked to better outcomes, yet m…

Opioid Use Disorder

Estimated

~$10 – $7,500

RTI InternationalNCT07214389

COMPASS: Correlative COMPAnion Study to Predict SYNERGY-201 Clinical Trial Responders

This study is a companion to the SYNERGY-201 clinical trial (NCT06228053), which investigates SX-682 and enzalutamide in individuals with prostate cancer. Indi…

Prostate Cancer

Estimated

~$10 – $750

Duke UniversityNCT07050433

Hematopoietic Cell Transplant and Gene Therapy for Non-Malignant Blood Disorders Biobank Resource (BMT CTN 2402)

A prospective, multicenter study that will establish a repository of biospecimens and clinical data from patients undergoing hematopoietic stem cell transplant…

Aplastic AnemiasHemoglobinopathiesBone Marrow Failure

Estimated

~$10 – $750

Medical College of WisconsinNCT07227155