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27,132 recruiting studies available now

Kabawil: Adapting an Intervention to Reduce Intersectional Stigmas Among Indigenous Sexual Minority Men and Traditional Healers in Mesoamerica

The goal of this study is to develop and test KABAWIL, a culturally tailored intervention designed to reduce HIV-related and intersectional stigmas experienced…

Stigma, Social

Estimated

~$10 – $6,250

University of WashingtonNCT07786441

Phase 1

Human Cerebrovascular Blood Flow and Sex Differences in Metabolic Syndrome

This study tests the hypothesis that Metabolic Syndrome (MetSyn) decreases cerebral blood flow (CBF) more in females than males due in part to the sex-specific…

Metabolic Syndrome

Estimated

~$10 – $6,250

University of Wisconsin, MadisonNCT07218653

Phase 2

A Phase II Multi-Center Open-label Randomized Study of CAPecitabine in Combination With ELAcestrant Versus Capecitabine Alone in Advanced Estrogen Receptor-Positive Breast Cancer (CAPELA)

The goal of this research study is to compare a combination of two drugs, capecitabine and elacestrant to capecitabine alone as a treatment for advanced estrog…

Estrogen-receptor-positive Breast CancerMetastatic Breast CancerBreast Cancer+6 more

Estimated

~$10 – $7,500

Kristina A. FanucciNCT07222215

Phase 3

A Phase III, Open-label, Randomised Study of Osimertinib With or Without Datopotamab Deruxtecan (Dato-DXd), as First-line Treatment in Participants With Epidermal Growth Factor Receptor (EGFR) Mutation-positive, Locally Advanced or Metastatic Non-small Cell Lung Cancer

The purpose of this study is to evaluate efficacy and safety of osimertinib (tablet) in combination with Dato-DXd (i.v. infusion) compared with osimertinib (ta…

Non-small Cell Lung Cancer

Estimated

~$10 – $7,500

AstraZenecaNCT06350097

Observational

Controlled Arterial Protection to Ultimately Remove Embolic Material

The objective of this study is to demonstrate safety and efficacy of the EmStop Embolic Protection System when used as indicated to capture and remove thrombus…

Aortic Valve StenosisAortic StenosisAortic Valve Disease

Estimated

~$10 – $8,750

EmStop IncNCT07276711

Phase 1

Hyperscan Neuroimaging to Reveal the Brain Mechanisms Supporting Analgesia Following MDMA-assisted Therapy for Fibromyalgia

Fibromyalgia is a debilitating chronic pain disorder. Based on prior research with MDMA, it can be hypothesized MDMA-assisted therapy in fibromyalgia patients …

Fibromyalgia

Estimated

~$10 – $6,250

Spaulding Rehabilitation HospitalNCT06066853

Observational

The Vira Platform: A Contextually Triggered Just-in-Time Adaptive Intervention for Opioid Use Disorder

Many patients stop medication-based treatments for Opioid Use Disorder (OUD) prematurely, placing them at increased risk for overdose and death. Providing targ…

Opioid Use DisordermHealthPeer Support

Estimated

~$10 – $6,250

Rhode Island HospitalNCT07778394

Phase 4

Efficacy of Potassium-Competitive Acid Blockers in Barrett's Esophagus (PCAB BE Study)

This is a research study to look at how a new medication compares to standard treatment for reducing acid reflux in patients with Barrett's Esophagus. The stud…

Barrett Esophagus

Estimated

~$10 – $6,250

University of North Carolina, Chapel HillNCT07788742

FEASIBILITY AND SAFETY OF INDOCYANINE GREEN (ICG) GUIDED SENTINEL LYMPH NODE MAPPING FOR PEDIATRIC SOLID TUMORS - T-LyM (Tumor-Lymph Node Mapping)

The purpose of this study is to assess the feasibility and safety of ICG-guided intraoperative lymphography for detecting sentinel lymph nodes (SLN) in pediatr…

Pediatric Solid TumorsRhabdomyosarcomaSarcoma+1 more

Estimated

~$10 – $750

University of RochesterNCT07054944

Observational

Let's Talk: Overcoming Barriers to Uptake of Cascade Screening Through a Stakeholder-informed Online Intervention

Lynch syndrome is a genetic condition that increases cancer risk. The public health impact of genetic testing for disease prevention hinges on cascade screenin…

Lynch Syndrome

Estimated

~$10 – $6,250

UNC Lineberger Comprehensive Cancer CenterNCT07304063

Phase 4

Evaluation of Dependence and Nicotine Replacement Therapy-Supported Cessation Efforts Among Regular Electronic Cigarette Use

This study aims to improve understanding of how people who use electronic cigarettes (ECIGs or e-cigarettes) respond when they try to stop using them and wheth…

E Cigarette UseCessation, TobaccoCessation, Nicotine

Estimated

~$10 – $6,250

West Virginia UniversityNCT07786896

Phase 2

A Phase 2 Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study to Evaluate the Efficacy and Safety of MK-2214 in Participants With Early Alzheimer's Disease

Researchers want to know if the study treatment called MK-2214 works to slow certain changes in the brains of people with Alzheimer's disease (AD). AD is a typ…

Early Alzheimer's Disease

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT07033494