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27,171 recruiting studies available now

Long-Term Tracking of Fluid Dynamics in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device During Activities of Daily Living Including Sleep

This study evaluates the performance of a device for non-invasively assessing cerebrospinal fluid (CSF) shunt flow over multiple measurements performed by a st…

Hydrocephalus

Estimated

~$10 – $8,750

Rhaeos, Inc.NCT07050628

Phase 3

Prospective Treatment of Types I, II and III Pleuropulmonary Blastoma (PPB)

This phase III trial tests how well surgery plus chemotherapy compared to surgery alone works in treating patients with type I pleuropulmonary blastoma (PPB), …

Pleuropulmonary Blastoma

Estimated

~$10 – $7,500

Children's Oncology GroupNCT06647953

Phase 1

A Pilot Presurgical Trial of REGN5678 (Anti-PSMA X CD28) in Patients With High-Risk, Localized Prostate Cancer Followed by Radical Prostatectomy

To learn about the safety and effects of a drug called REGN5678 when it is given to patients with high-risk prostate cancer.

Prostate CancerRadical Prostatectomy

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT06085664

Observational

Practical Geriatric Assessment in Older Adults With Non-Small Cell Lung Cancer Undergoing Stereotactic Body Radiation Therapy

National guidelines recommend that older adults with cancer undergo a special health assessment before starting cancer treatment. This type of assessment evalu…

Lung Cancer (NSCLC)Geriatric AssessmentStereotactic Body Radiation Therapy (SBRT)

Estimated

~$10 – $6,250

Brigham and Women's HospitalNCT06987890

Unified Network for Integrated Fluid Collection at Yale

UNIFY is a Yale-wide liquid biopsy master repository that prospectively collects Streck-tube blood, dried blood spots (and optional archival tissue) from Yale …

Molecular Residual DiseaseCancer

Estimated

~$10 – $750

Yale UniversityNCT07689864

Phase 3

A PHASE 3, MULTI-CENTER, OPEN-LABEL EXTENSION STUDY TO INVESTIGATE THE LONG-TERM SAFETY, TOLERABILITY, AND EFFICACY OF DAZUKIBART IN PARTICIPANTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES (INCLUDING PARTICIPANTS WITH DERMATOMYOSITIS OR POLYMYOSITIS)

The purpose of this study is to understand how the study medicine, dazukibart, works in people with active idiopathic inflammatory myopathies (dermatomyositis …

DermatomyositisPolymyositis

Personalized Fluid Resuscitation for Improved Sepsis Resuscitation Quality in the Emergency Department

The goal of this pilot clinical trial is to learn if a fluid assessment using non-invasive cardiac output monitoring (NICOM) is helpful for patients with sepsi…

SepsisSeptic Shock

Estimated

~$10 – $8,750

Intermountain Health Care, Inc.NCT07779720

Phase 3

A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients With Germ Cell Tumors

This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is r…

Childhood Extracranial Germ Cell TumorExtragonadal Embryonal CarcinomaGerm Cell Tumor+27 more

Phase 3

A Phase 3 Randomized Trial of Inotuzumab Ozogamicin (IND#:133494, NSC#: 772518) for Newly Diagnosed High-Risk B-ALL; Risk-Adapted Post-Induction Therapy for High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and Disseminated B-LLy

This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy and immunotherapy (chemo-immunotherapy) for patients with High-…

B Acute Lymphoblastic LeukemiaB Lymphoblastic LymphomaCentral Nervous System Leukemia+2 more

Estimated

~$10 – $7,500

Children's Oncology GroupNCT03959085

Observational

Evaluation of Fatigue and Mitigations During Long-haul Operations

The purpose of the present study is to test novel countermeasures to reduce fatigue among airline pilots during long-haul flight operations. The investigators …

Alertness, Fatigue, Mood, and PerformanceCalorie Restriction and Light Intervention

Estimated

~$10 – $7,500

National Aeronautics and Space Administration (NASA)NCT07761611

Long-Term Outcomes of Participants Treated With Teplizumab in Routine Clinical Care

This is an observational, prospective cohort study designed to evaluate the outcomes after teplizumab treatment in participants with Stage 2 Type 1 Diabetes (T…

Precision Neoadjuvant Therapy for High Risk Localized Prostate Cancer With PTEN Loss

The purpose of this study is to learn about how an investigational drug intervention completed before doing prostate surgery (specifically, radical prostatecto…

High-Risk Prostate Cancer

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT05593497