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25,453 recruiting studies available now

RASolute 304: A Phase 3 Multicenter, Open-label, Randomized, 2-Arm Study of Adjuvant Daraxonrasib Versus Standard of Care Observation Following Completion of Neoadjuvant and/or Adjuvant Chemotherapy in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard of care (SOC) observation only.

Pancreatic CancerPDACPDAC - Pancreatic Ductal Adenocarcinoma+2 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Revolution Medicines, Inc.NCT07252232

Breast Radiation-induced Immunologic Genomic Hypofractionated Temporal Radiation Alterations DNA Damage (BRIGHT-RAD) Study.

This study assesses changes to the immune cells following hypofractionated radiation-induced DNA damage in breast cancer patients. Radiation therapy may cause …

Breast CarcinomaInvasive Breast Carcinoma

Estimated

~$10 – $750

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT05406232

Prospective, Multicenter, Observational Study to Evaluate the Merit WRAPSODY® Cell Impermeable Endoprosthesis for Treatment of Stenosis or Occlusion Within the Dialysis Outflow Circuit (WRAP North America)

The goal of this observational study is to investigate the safety and efficacy of the WRAPSODY CIE in a real-world North American population. Participants trea…

Venous StenosisVenous Occlusion

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Merit Medical Systems, Inc.NCT06807099

Phase 2

An Outpatient, Randomized, Double-Blinded, Placebo-Controlled, Cross-Over Study of the Efficacy of ARS-2 in Patients With Chronic Spontaneous Urticaria

This is a Phase 2b, outpatient, single-dose, randomized, double blind, placebo-controlled, three period crossover study that will consist of a screening period…

Urticaria Chronic

Estimated

~$75 – $2,800

Actual pay is set by the research site.

ARS Pharmaceuticals, Inc.NCT06927999

Phase 4

Comparison of Remimazolam Versus Propofol for Monitored Anesthetic Care in Elective Fractional Ablative CO₂ Laser

This randomized, single-blind, crossover study compares remimazolam and propofol for monitored anesthetic care during fractional ablative CO₂ laser therapy for…

Burn ScarHypertrophic ScarringProcedural Sedation

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Medical University of South CarolinaNCT07213544

Phase 4

A Prospective, Multi-Center, Randomized, Open Label Trial to Determine if a Common Atrial Fibrillation Risk Locus Modulates Differential Response to Antiarrhythmic Drugs

In this pilot and feasibility study, the investigators will enroll patients with frequent symptomatic episodes of atrial fibrillation (AF) in a cross-over stud…

Atrial Fibrillation

Estimated

~$25 – $1,000

Actual pay is set by the research site.

University of Illinois at ChicagoNCT02347111

Phase 1

A Phase 1, Multicenter, Open-label, Non-randomized, Dose-escalation and Backfill Study of KK2223 in Participants With Relapsed or Refractory T-cell Non Hodgkin Lymphoma

The purpose of this study is to determine the safety, tolerability, PK and pharmacodynamics of KK2223 in adult participants with relapsed or refractory periphe…

T-cell NHL (PTCL or CTCL)

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Kyowa Kirin, Inc.NCT07192471

Observational

Assessment of Fall Risks and Subject-specific Training for Fall Reduction

The target population of this project is older people with high risks of falls. About 30% community-dwelling individuals over 65 years of age fall each year an…

Fall Risk

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Maryland, BaltimoreNCT06396650

Phase 1

First-in-human, Open-label, Phase 1 Trial to Evaluate the Safety and Preliminary Efficacy of GEN1079 in Participants With Select Advanced Malignant Solid Tumors

The purpose of this trial is to learn about the safety and effectiveness of the antibody GEN1079 in participants with certain types of cancer. The trial has m…

Advanced Solid Tumors

Estimated

~$150 – $4,500

Actual pay is set by the research site.

GenmabNCT07387068

Phase 1

A Phase 1 Study of JNJ-87189401 (PSMA-CD28 Bispecific Antibody) Combined With JNJ-78278343 (KLK2-CD3 Bispecific Antibody) for Advanced Prostate Cancer

The purpose of Parts 1, 2A, and 2B of the study is to determine the recommended regimen for Phase 2 (RP2Rs) of combination of JNJ-87189401 with JNJ-78278343 an…

Prostatic Neoplasms

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Janssen Research & Development, LLCNCT06095089

Observational

The Effects of Trauma-focused Psychotherapy on Reward Circuitry Function and Information Encoding

The purpose of this study is to identify how trauma-focused psychotherapy changes the function of brain circuitry in posttraumatic stress disorder (PTSD) and h…

Post Traumatic Stress DisorderDiminished PleasureAnhedonia+3 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Texas at AustinNCT06096740

Observational

Efficacy & Safety of LOBO™ Vascular Occlusion Device for Embolization of Pulmonary Arteriovenous Malformations (PAVM)

The goal of this clinical trial is to evaluate both the technical success and efficacy of using the LOBO™ device in patients undergoing embolization of Pulmona…

Pulmonary Arteriovenous Malformations

Estimated

~$10 – $750

Actual pay is set by the research site.

University of North Carolina, Chapel HillNCT06735976