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27,258 recruiting studies available now

A Prospective, Longitudinal, Observational, Multi-centre Study of Pediatric Participants up to 16 Years of Age With Methylmalonyl-CoA Mutase Deficiency Caused by Mutations in the MMUT Gene That Results in a Diagnosis of Isolated Methylmalonic Acidemia (MMA).

Methylmalonic Acidemia (MMA) is a severe and rare condition that affects how the body turns food into energy. In people with MMA, the body is missing or has a …

Methylmalonic Acidemia (MMA)

Estimated

~$10 – $1,125

Genespire SrlNCT07432880

Artificial Intelligence-Based Phenotyping of Health From Photographs - Healthy Volunteer Study

The investigators aim to examine how FaceAge estimates (a measure of biological age based on facial features) change across different time points and identify …

AgingFacial Aging

Estimated

~$10 – $750

Brigham and Women's HospitalNCT07719049

Phase 1

A Phase 1/2 Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

The purpose of this study is to assess the safety, tolerability, and recommended dose(s) of BMS-986340 as monotherapy and in combination with nivolumab, doceta…

Cervical CancerGastric/Gastroesophageal Junction AdenocarcinomaMicrosatellite Stable Colorectal Cancer+8 more

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT04895709

Phase 2

A Phase 1/2, Open-Label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T Cells (CABA-201) in Subjects With Systemic Sclerosis

RESET-SSc: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T cell therapy, in Subjects with Systemic Sclerosis

Systemic SclerosisSclerodermaInterstitial Lung Diseases

Estimated

~$10 – $7,500

Cabaletta BioNCT06328777

The Gut Microbiome and Serum Metabolites as a Biological Mechanism Underlying Pain in Kidney Transplantation (Biome-KT)

Study Summary Nearly half (47%) of people with end-stage kidney disease (ESKD) whose kidney function is restored after kidney transplantation experience chroni…

Kidney Transplant SymptomsGut Microbiome

Estimated

~$10 – $750

University of Illinois at ChicagoNCT06206486

Phase 2

A Randomized, Masked, Placebo Controlled, Phase II Trial Of Concurrent Chemoradiation With BMX-001 In Patients With Head And Neck Squamous Cell Carcinoma Receiving Concurrent Chemoradiation

This phase II trial compares the effectiveness of adding BMX-001 to usual symptom management versus usual symptom management alone for reducing oral mucositis …

Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+38 more

Phase 2

A Single-arm Open-label Study Assessing Efficacy of Bimekizumab in Adult Participants With Pyoderma Gangrenosum Over 24 Weeks

The purpose of the study is to learn more about an experimental drug bimekizumab that may be helpful for Pyoderma Gangrenosum (PG). Bimekizumab will be referre…

Pyoderma Gangrenosum

Estimated

~$10 – $6,250

Oregon Health and Science UniversityNCT07767864

Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients With Sickle Cell Disease

Background: Some people with the same disorder on a genetic level have more complications than others. Researchers want to look for a link between the PKLR ge…

Sickle CellPKLR VariantsAdenosine Triphosphate Activities

Estimated

~$10 – $675

National Heart, Lung, and Blood Institute (NHLBI)NCT03685721

Observational

Evaluation of Novel Woven Fabric Radiation Protection Gear for Head and Neck Regions for Interventional Radiology Personnel

This study will use procedure-specific dosimetry to evaluate whether Texray's novel woven radiation protection fabric (HeadPeace and MindPeace) reduces occupat…

Radiation Exposure

Estimated

~$10 – $6,250

Emory UniversityNCT07768605

Phase 1

Monitoring Breast Cancer Immunotherapy Treatment With Advanced PET/MRI: A Pilot Study

This clinical study will investigate the utility of Fludeoxyglucose (18F) fluoromisonidazole (FMISO), in patients diagnosed with triple negative breast cancer …

Triple Negative Breast Cancer

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT04861077

Phase 1

A Phase I First-in-human, Open-label, Multicenter Study to Investigate the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0505 in Adult Participants With Advanced Solid Tumors

This is an open-label, multicenter phase 1 study to evaluate the safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0505 in Adult …

Advanced Solid TumorsPlatinum Resistant Ovarian CancerFallopian Tube Cancer+5 more

Estimated

~$10 – $8,750

NextCure, Inc.NCT06792552

Phase 3

Light for Ulcer Management by Infection Elimination and Resistance Enhancement (LUMIERE)

This is a multicenter trial with recruitment planned at ophthalmology clinics specializing in corneal diseases in India, Brazil, and at Stanford University and…

Fusarium Keratitis

Estimated

~$10 – $6,250

Stanford UniversityNCT07743489