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A Multi-Modal Wearable Sensor for Early Detection of Cognitive Decline and Remote Monitoring of Cognitive-Motor Decline Over Time

This observational study will enroll approximately 100 participants evenly split by cognitive status (Cognitively Impaired vs Non-Cognitively Impaired), and in…

Mild Cognitive Impairment (MCI)Older Adults With Cognitive DeclineOlder Adults

Estimated

~$10 – $1,125

BioSensicsNCT07780162

Phase 4

Neurovascular Effects of Empagliflozin in Mid-Life and Older Adults With Prehypertension

The goal of this clinical trial is to examine whether empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, improves vascular and autonomic funct…

Blood PressureEndothelial Dysfunction

Estimated

~$10 – $7,500

Kanokwan BunsawatNCT07799441

Phase 3

A Randomized, Double-Blind, Active-Control, Multicenter Phase 3 Trial of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

The purpose of the study is to evaluate the progression-free survival (PFS) of casdatifan versus placebo when each is given in combination with cabozantinib in…

Metastatic Clear Cell Renal Cell CarcinomaAdvanced Clear Cell Renal Cell Carcinoma

Estimated

~$10 – $8,750

Arcus Biosciences, Inc.NCT07011719

Phase 3

A Phase III, Multi-center, Open-label, Randomised, Controlled Trial of Intravenous Obrixtamig in Combination With Carboplatin and Etoposide vs. Carboplatin and Etoposide as First-line Therapy in DLL3-positive Patients With Unresectable Locally Advanced or Metastatic Extrapulmonary Neuroendocrine Carcinomas

This study is open to adults with advanced extrapulmonary neuroendocrine cancer. The purpose of this study is to find out if a study medicine called obrixtamig…

Extrapulmonary Neuroendocrine Cancer (epNEC)

Estimated

~$10 – $7,500

Boehringer IngelheimNCT07544654

Phase 2

PODOMOUNT-Basket, a Phase II, Multicentre, Randomised, 2-arm Parallel-group, Double-blind, Placebo-controlled Basket Trial to Assess Safety, Tolerability, PK, and Efficacy of BI 764198 in Four Proteinuric Kidney Diseases

This study is open to adults with certain kidney conditions, including secondary focal segmental glomerulosclerosis (sFSGS), treatment-resistant primary minima…

Proteinuric Kidney Diseases

Estimated

~$10 – $7,500

Boehringer IngelheimNCT07355296

Phase 1

Phase 1 Study of ChoironeX GalKO Porcine Thymokidney Xenotransplantation in End-Stage Renal Disease

The goal of this clinical trial is to learn if a GalKO Porcine Thymokidney can maintain renal function, without the need for dialysis, after transplantation in…

End Stage Renal Disease

Estimated

~$10 – $8,750

Xeno Holdings (US), LLC dba ChoironeXNCT07696962

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

The TEMPUS AQUARIUS Study is a non-interventional, longitudinal observational study focused on hematological malignancies. It will collect rich molecular (mult…

Acute Myeloid Leukaemia (AML)Follicular Lymphoma ( FL)

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of DNTH103 In Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)

The purpose of this Phase 3 study is to demonstrate the efficacy of claseprubart (DNTH103) as compared to placebo in participants with chronic inflammatory dem…

Chronic Inflammatory Demyelinating Polyneuropathy

Estimated

~$10 – $8,750

Dianthus TherapeuticsNCT06858579

Microbiome in Aging Gut and Brain (MiaGB) Study

The Microbiome in Aging Gut and Brain (MiaGB) Study is an observational study designed to examine whether differences in the microorganisms living in the gut a…

Mild Cognitive ImpairmentAlzheimer Disease (AD)Dementia

Estimated

~$10 – $750

University of South FloridaNCT07799402

Observational

Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)

The goal of this clinical trial is to evaluate the safety and preliminary efficacy of an implantable device that records and stimulates different areas of the …

Tetraplegia/TetraparesisAmyotrophic Lateral Sclerosis (ALS)Muscular Disorders, Atrophic+6 more

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT07521930

Phase 3

Early Reinitiation of Semaglutide Post-Sleeve Gastrectomy in Youth: A Randomized Clinical Trial

This is a Phase 3a, randomized, parallel-controlled trial designed to compare the early re-initiation of semaglutide, starting two weeks after sleeve gastrecto…

Pediatric ObesityMetabolic and Bariatric SurgerySemaglutide

Estimated

~$10 – $6,250

Children's Hospital Los AngelesNCT06934655

Phase 2

Combination Therapy Using Durvalumab and Histotripsy for Treatment of Intrahepatic Cholangiocarcinoma (CODAH Trial)

The purpose of this research is to evaluate whether adding histotripsy to maintenance durvalumab increases immune response and to assess the safety of this com…

Intrahepatic Cholangiocarcinoma

Estimated

~$10 – $6,250

University of Wisconsin, MadisonNCT07766187