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Open-label Randomized, Three-fold Cross-over, Single-center Interaction Study to Investigate the Influence of Multiple Doses of Acetylsalicylic Acid (ASA) (Aspirin) on the Pharmacodynamics of BAY 3389934 in Healthy Participants.

The study treatment BAY3389934 is under development for people with blood clotting problems that occur due to sepsis. Sepsis is a serious condition that happen…

Drug-drug Interaction

Estimated

~$500 – $11,250

Actual pay is set by the research site.

BayerNCT07652723

Phase 1

Window of Opportunity Study of Lixumistat in Patients With Newly Diagnosed Glioblastoma

The purpose of this study is to determine the effect of Lixumistat in patients with newly diagnosed Glioblastoma.

Glioblastoma

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Macarena De La Fuente, MDNCT07884344

Phase 2

An Open-label, Single-Arm, Phase 2 Study to Evaluate Enfortumab Vedotin Plus Pembrolizumab for Bladder Preservation in Participants With Muscle-invasive Bladder Cancer (EV-209)

People with a type of bladder cancer called muscle-invasive bladder cancer have cancer that has spread into the muscle wall of the bladder. The standard treatm…

Muscle-invasive Bladder Cancer

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Astellas Pharma Global Development, Inc.NCT07475806

Phase 1

A Phase1 b/2, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of GSK5764227 Alone and in Combination in Participants With Previously Treated Advanced Unresectable or Metastatic Gastrointestinal Solid Tumors

This study will check how well a new medicine, Risvutatug rezetecan, (Ris-Rez, also known as GSK5764227) works, how safe it is and how the body handles it in p…

Gastrointestinal Neoplasms

Estimated

~$150 – $4,500

Actual pay is set by the research site.

GlaxoSmithKlineNCT06885034

Phase 3

A Randomized Phase 3 Interim Response Adapted Trial Comparing Standard Therapy With Immuno-oncology Therapy for Children and Adults With Newly Diagnosed Stage I and II Classic Hodgkin Lymphoma

This phase III trial compares the effect of adding immunotherapy (brentuximab vedotin and nivolumab) to standard treatment (chemotherapy with or without radiat…

Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Estimated

~$50 – $1,350

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT05675410

Phase 3

A Phase 3, Global, Multi-center, Double-blind, Randomized Study of ASP2138 Plus Chemotherapy (CAPOX or mFOLFOX6) With Pembrolizumab vs Placebo Plus Chemotherapy With or Without Pembrolizumab in First-line Treatment of Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma in Participants Whose Tumors Are HER2-negative and Claudin (CLDN) 18.2-positive

Claudin 18.2 or CLDN18.2 is a protein found on cells in the digestive system. It is also found in some tumors. Researchers are looking at ways to attack CLDN18…

Gastric AdenocarcinomaGastroesophageal Junction (GEJ) Adenocarcinoma

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Astellas Pharma Global Development, Inc.NCT07673887

Quality of Pediatric Resuscitation in a Multicenter Collaborative: An Observational Study

This is a prospective, observational, multi-center cohort study of pediatric cardiac arrests. The purpose of the study is to determine the association between…

Cardiac ArrestCardiopulmonary Arrest

Estimated

~$10 – $750

Actual pay is set by the research site.

Children's Hospital of PhiladelphiaNCT02708134

Phase 3

A Phase 3 Study to Investigate the Efficacy and Safety of LY900043 in Adult Participants With Obesity or Overweight and Type 2 Diabetes

The purpose of this study is to investigate the efficacy and safety of eloralintide and tirzepatide coformulation (EloraTZP) compared to tirzepatide for body w…

ObesityOverweightDiabetes Mellitus, Type 2

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Eli Lilly and CompanyNCT07881458

Observational

REACT: A Just-in-Time Adaptive Intervention to Reduce Reactive Digital Behavior in College Students

This study looks at the moments when college students feel a strong emotional swing, and how those moments relate to reacting online when upset, drinking alcoh…

Emotional RegulationAlcohol Drinking in CollegeEmotional Eating+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of FloridaNCT07789314

Observational

I CARE (Immunotherapy Cutaneous Adverse Events REsearch) - A Trial With Diverse Cancer Patients to Determine the Impact of SDoH and Side Effects Navigation Program on Treatment Continuation

The purpose of this study is to find out if the navigation program helps participants manage immunotherapy treatment better than usual care. Investigators will…

Kidney CancerBladder CancerBreast Cancer+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT07646847

An Observational Study of Genetic Cardiomyopathy, Danon Disease

The goal of this international observational study is to learn about the natural history of Danon disease in male patients (≥8 years of age) and female patient…

Danon Disease

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Rocket Pharmaceuticals Inc.NCT06214507

Phase 2

Immunogenicity and Safety of Consecutive High-Dose vs. Standard-Dose Influenza Vaccines Administered Over Successive Seasons in Lung Transplant Recipients

This will be a follow-up study to the "Comparison of High Dose vs. Standard Dose Influenza Vaccine in Lung Allograft Recipient" study (DMID Protocol Number 22-…

Immunization; Infection|Transplantation Infection|InfluenzaInfluenza

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Vanderbilt University Medical CenterNCT07192458