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Feasibility and Pilot Study Testing an Online Digital Intervention to Improve Symptom Management During Breast Cancer Chemotherapy

This trial tests an online nutrition education program focused on decreasing nutrition-related side effects of chemotherapy in patients with breast cancer. Pat…

Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8

Estimated

~$10 – $6,250

Fred Hutchinson Cancer CenterNCT05874297

Phase 1

A Phase 1, Open-Label Study to Evaluate the Safety, Biodistribution, Imaging Characteristics, and Radiation Dosimetry of [18F]LY4214835 in Healthy Volunteers and Participants With Cancer

The purpose of the study is to check how safe and well-tolerated \[18F\]LY4214835 injection is in healthy participants and participants with cancer. The study …

NeoplasmsHealthy

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07258836

Phase 2

SMART-PANC: SMAD4 Tailored Neoadjuvant Therapy for Pancreatic Cancer, A Phase ll Non-Randomized, Single Center Pilot Study

This phase II trial tests the impact of using SMAD4-mutant status to personalize chemotherapy in treating patients with pancreatic ductal adenocarcinoma (PDAC)…

Borderline Resectable Pancreatic Ductal AdenocarcinomaResectable Pancreatic Ductal Adenocarcinoma

Estimated

~$10 – $6,250

Northwestern UniversityNCT07748611

Phase 1

IT2023-08-ATKINS-ATHERO-RT: Real-Time Atherosclerosis Activity After Thoracic Radiotherapy Using Sodium Fluoride Positron Emission Tomography

The prospective single-arm pilot study, ATHERO-RT: Real-Time Atherosclerosis Activity after Thoracic Radiotherapy using Sodium Fluoride Positron Emission Tomog…

Oligometastatic Disease

Estimated

~$10 – $7,500

Katelyn AtkinsNCT06373497

Observational

Microvideos for Improving HPV Vaccination Among Childhood Cancer Survivors

This exploratory mixed-methods study aims to examine receipt of treatment and decision-making among rural cancer patients in Utah. Guided by Conceptual Model o…

HPV Vaccination

Estimated

~$10 – $6,250

University of UtahNCT07648953

NIS103487 Duration of Streptococcus Pneumoniae Carriage in U.S. Children Under Five: A Pilot Longitudinal Study

Streptococcus pneumoniae (SPN) remains a leading cause of respiratory disease in young children despite widespread vaccination. Understanding the duration of p…

Pneumococcal Carriage

Estimated

~$10 – $750

University of Central FloridaNCT07748832

Observational

Cognitive Rehabilitation for Treatment of Anger in Veterans With TBI (Traumatic Brain Injury) and PTSD (Post-traumatic Stress Disorder)

This randomized clinical trial will enroll 100 Veteran-family/friend dyads to test the efficacy of CALM in treating anger in TBI and PTSD. The investigators hy…

Traumatic Brain Injury (TBI)Posttraumatic Stress Disorder (PTSD)

Estimated

~$10 – $6,250

Duke UniversityNCT07227987

Observational

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity-Associated Diseases

The goal of this study is to evaluate the role of transcription factor EB (TFEB) in adipose (fat) tissue macrophages (ATM) in regulating adipose tissue and sys…

ObesityNonalcoholic Fatty LiverDiabetes Type 2+1 more

Estimated

~$10 – $7,500

Bettina MittendorferNCT06335771

Phase 1

Phase I, Open-Label Study of Autologous Mutant KRAS and ILT4-Redirected T-cell Receptor Cells (TCR1188-ABC)

This is a Phase I, open-label dose finding study to assess the safety, manufacturing feasibility, and preliminary efficacy of TCR1188-ABC cells in patients wit…

CholangiocarcinomaColorectal CancerNon-Small Cell Lung Cancer+1 more

Estimated

~$10 – $6,250

University of PennsylvaniaNCT07594067

Phase 4

Study Testing Outcomes After Planned Discontinuation of AntiSeizure Medication

The main purpose of this study is to understand the effects of continuing versus discontinuing antiseizure medications after a period of seizure-freedom. Physi…

Epilepsy

Estimated

~$10 – $6,250

University of MichiganNCT07750496

Project CONTINUITY: Promoting Evidence-Based Cancer Screening Among Underserved Women

Project CONTINUITY (Connecting You to Care in the Community) was developed to increase adherence to cervical cancer screening regimens from initial screening t…

Cervical Cancer Screening Methods

Estimated

~$10 – $750

University of FloridaNCT05390567

Phase 4

The Effects of Soluble Guanylyl Cyclase Stimulation on Perioperative Vascular Reactivity and Organ Injury in Cardiac Surgery

The goal of this mechanistic clinical trial is to learn about the effects of medications called soluble guanylyl cyclase stimulators on vascular function and m…

Endothelial DysfunctionVascular DiseasesKidney Injury+2 more

Estimated

~$10 – $6,250

Vanderbilt University Medical CenterNCT05812755