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Autologous IC-Nine, CD30 CAR, and Constitutive IL7R Expressing EBVST for CD30 Lymphoma (ANCILE-30)

This Phase I study will evaluate the safety of autologous Epstein-Barr virus-specific T lymphocytes modified to express a constitutively active IL7 receptor (C…

Diffuse Large B-Cell Lymphoma (DLBCL)Hodgkin LymphomaPeripheral T-cell Lymphoma (PTCL)+2 more

Estimated

~$10 – $6,250

The Methodist Hospital Research InstituteNCT07729397

Observational

Randomized Controlled Trial of Mantram Repetition Program Versus Health and Wellness Psychoeducation for Veterans With Comorbid Posttraumatic Stress Disorder and Chronic Pain

Approximately 450,000 Veterans Health Administration service users have both posttraumatic stress disorder (PTSD) and chronic pain (CP); treatments that effici…

Stress Disorders, Post-TraumaticPain, Chronic

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT07725588

Detection of Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors Exposed to Cisplatin-based Chemotherapy and Bone Marrow Transplant

Late subclinical cardiovascular disease in testicular cancer survivors exposed to cisplatin-based chemotherapy and bone marrow transplant

Testicular CancerSurvivorshipASCVD+5 more

Estimated

~$10 – $750

Indiana UniversityNCT05611307

Observational

A Novel Acceptance-based Treatment for Insomnia in Veterans With Post-Traumatic Stress Disorder

This randomized trial will compare a novel treatment, Acceptance of the Behavioral Changes to Treat Insomnia (ABC-I) to Cognitive Behavioral Therapy for Insomn…

InsomniaPTSD

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT05194930

Phase 2

A Randomized, Double Blind, Placebo Controlled, Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With Major Depressive Episodes Associated With Bipolar I Disorder

Phase II study for patients with Bipolar 1 Disorder experiencing major depressive episode. Patient eligible for enrollment will be randomized (like flipping a …

Bipolar I Disorder

Estimated

~$10 – $8,750

LB Pharmaceuticals Inc.NCT07494305

Phase 2

A Phase II Randomized Study of Safety and Efficacy of a Multiple Antigen Vaccine (STEMVAC) in Non-Small-Cell Lung Cancer Patients

This phase II trial tests whether CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope plasmid DNA vaccine (STEMVAC) works to shrink tumors in patients with stage IV non-smal…

Lung Non-Small Cell CarcinomaStage IV Lung Cancer AJCC v8

Estimated

~$10 – $6,250

University of WashingtonNCT05242965

Observational

Adaptive Mobile Interventions to Reduce Cancer Risk Behaviors

Tobacco use remains the leading cause of preventable death, causing over 400,000 annual deaths in the United States alone. Smartphone-based interventions, part…

Smoking Cessation

Estimated

~$10 – $5,625

Johns Hopkins Bloomberg School of Public HealthNCT07585357

Phase 1

PAIN-GP: Project Assessing the Mechanisms and Impact of a Novel Cannabinoid Product for Gynecologic Pain

Despite recent increases in both medical and recreational cannabis use in the United States and globally, little research has been conducted to determine the p…

EndometriosisAdenomyosisChronic Pelvic Inflammatory Disease

Estimated

~$10 – $7,500

Staci Gruber, Ph.D.NCT07728695

Observational

Building Cognitive Reserve Through Brain-Computer-Interfaces

Cognitive reserve refers to the brain's ability to maintain cognitive performance despite age-related changes or neuropathology. Enhancing cognitive reserve is…

Mild Cognitive Impairment (MCI)

Estimated

~$10 – $6,250

University of Texas at AustinNCT07441122

Phase 1

Early Phase Study to Evaluate the MEK Inhibitor Selumetinib With the MDM2 Inhibitor APG-115 in Patients With Neurofibromatosis Type 1 and Pre-malignant and Malignant Peripheral Nerve Sheath Tumors

This is a phase 0/1/2, multi-site study to evaluate the MEK inhibitor Selumetinib with the MDM2 Inhibitor APG-115 in patients with Neurofibromatosis Type 1 and…

Malignant Peripheral Nerve Sheath Tumor (MPNST)Neurofibromatosis 1 (NF1)Atypical Neurofibroma

Estimated

~$10 – $7,500

AeRang KimNCT06735820

Phase 2

Sit Less, Interact and Move More (SLIMM) 2 Study

* Prolonged sitting (sedentary behavior) is a risk factor for decreased kidney function, obesity, diabetes and mortality. Prolonged sitting is associated with …

Chronic Kidney DiseasesObesity

Estimated

~$10 – $7,500

Srinvasan BeddhuNCT05173714

Phase 1

A Phase 1a/1b, Multicenter, Open-Label, First-in-Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of DB-1317 in Participants With Selected Advanced/Metastatic Solid Tumors

This is a multicenter, open-label, multiple-dose, FIH Phase 1a/1b study. Phase 1a adopts an accelerated titration design and a BOIN design to identify the MTD …

Advanced/Metastatic Solid Tumors

Estimated

~$10 – $8,750

DualityBio Inc.NCT07141706