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A Phase 1 Study of Avapritinib in Combination With Decitabine in Patients With Systemic Mastocytosis With an Associated Hematologic Neoplasm (SM-AHN)

Systemic mastocytosis with an associated hematologic neoplasm (SM-AHN) is a challenging disease to treat. Targeted KIT inhibitors have been approved for this i…

Systemic Mastocytosis With an Associated Hematologic Neoplasm

Estimated

~$150 – $3,000

Actual pay is set by the research site.

H. Lee Moffitt Cancer Center and Research InstituteNCT06327685

Observational

Digestion and Transit of Food DNA Through the Human Gut

This pilot study investigates the digestion rate of naturally occurring food DNA through the human digestive tract by detecting residual food DNA in stool samp…

Digestion Rate

Estimated

~$10 – $750

Actual pay is set by the research site.

Duke UniversityNCT06687226

Observational

Protective Benefits of a Clear Liquid Diet on Residual Gastric Content in Patients Taking Glucagon Like Peptide-1 Receptor Agonist Prior to Anesthesia

The purpose of this study is to determine if prolonged fasting from solids and transitioning to a CLD for 24 hours is protective to decrease RGC in patients on…

Pulmonary Aspiration

Estimated

~$10 – $750

Actual pay is set by the research site.

The University of Texas Health Science Center, HoustonNCT06654219

Phase 3

Randomized, Prospective, Open-label, Controlled Trial of 0.5% Bupivacaine Lower Cervical Intramuscular Injection vs IV Medications in Treatment of Non-Traumatic Headache in the Emergency Department

Headache is a frequent chief complaint among patients presenting to the Emergency Department (ED), accounting for 2.1 million visits annually in the United Sta…

HeadacheMigraineTension Headache+1 more

Estimated

~$50 – $1,500

Actual pay is set by the research site.

HCA Florida North Florida HospitalNCT06937385

Phase 1

A Phase Ib/Phase II Trial With Capivasertib Plus Immunotherapy in Bladder Cancer

This study aims to determine whether adding an oral medication called Capivasertib to ongoing immunotherapy can enhance treatment responses in patients with ad…

Advanced Urothelial Carcinoma

Estimated

~$150 – $2,700

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT07793578

Phase 1

Cocoa to Maximize Exercise Training in Older Adults - The COMET Trial

The purpose of the study is to see if regular exercise when combined with a cocoa supplement will improve physical performance and muscle strength compared to …

Mobility Disability

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of Alabama at BirminghamNCT07161726

Phase 1

A Phase I Trial of CRD3874-SI, a STING Agonist, in Patients With Advanced/Metastatic Malignant Solid Tumors

This study will test the safety of a study drug called CRD3874-SI. The researchers will test different doses of CRD3874-SI to find the highest dose that causes…

SarcomaMerkel Cell Carcinoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT06021626

DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With Transthyretin-Mediated Amyloidosis With Cardiomyopathy in a Real-World Setting

The purpose of this study is to: * Describe the clinical characteristics of adult patients with transthyretin-mediated amyloidosis with cardiomyopathy (ATTR-C…

Transthyretin Amyloidosis With Cardiomyopathy

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Alnylam PharmaceuticalsNCT07358078

Phase 4

Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

Single center, prospective, Open label study of sleep, pruritus and circadian function pre/post 12-weeks of dupilumab treatment in children 6-17 years old

Atopic DermatitisSleep Disturbance

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Northwestern UniversityNCT05042258

Observational

Adaptation of Helping Ovarian Cancer Patients Cope (HOPE) for Clinician Burnout (HOPE-C)

This clinical trial tests an adapted version of the Helping Ovarian Cancer Patients Cope (HOPE) intervention to address burnout among gynecologic oncology clin…

Ovarian CarcinomaPsychiatric Disorder

Estimated

~$10 – $750

Actual pay is set by the research site.

Fred Hutchinson Cancer CenterNCT07282158

Acceptability of Testing DNA Markers in Vaginal Fluid for the Detection of Endometrial Cancer

This study evaluates how women feel about using DNA from a vaginal fluid collection for early detection of endometrial cancer.

Endometrial Carcinoma

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT07527143

Pharmacogenetic Determinants Of Treatment Response In Children

To investigate whether genetic polymorphisms in genes encoding proteins involved in the metabolism or effects of drugs or environmental agents influence the di…

All MalignanciesChildren Being Treated for Catastrophic Illness

Estimated

~$10 – $750

Actual pay is set by the research site.

St. Jude Children's Research HospitalNCT00730678