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26,914 recruiting studies available now

Parents Helping Parents for Youth Vaping Cessation (PhP-VX)

The goal of this randomized controlled study is to test if this new intervention works to help adolescents quit vaping. A key feature of the program is the use…

Implementation ScienceEngagement, PatientE Cigarette Use+4 more

Estimated

~$10 – $6,250

University of NebraskaNCT07207850

Phase 1

A Phase I/Ib Study of Losartan in Combination With Sunitinib in the Treatment of Pediatric and Adult Patients With Relapsed or Refractory Osteosarcoma

This study is a Phase 1/1b clinical trial that aims to determine the Maximally Tolerated Dose of Losartan and Sunitinib Combination Therapy. Patients will firs…

Osteosarcoma

Estimated

~$10 – $6,250

University of Colorado, DenverNCT03900793

Remote eligible

A Natural History Study of the Immune Regulation of Idiopathic Inflammatory Bowel Diseases: Crohn's Disease, Ulcerative Colitis, and Other Inflammatory Conditions of the Gut

This study will investigate in patients with Crohn s disease and ulcerative colitis how the body s immune system controls inflammation in the gastrointestinal …

Inflammatory Bowel DiseaseUlcerative ColitisChrohn's Disease

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT00001184

Phase 2

A Phase 2a Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS Patients

Background: Autoimmune lymphoproliferative syndrome (ALPS) is a rare disorder of the immune system caused by a mutation in the FAS gene. In ALPS, the body sto…

Autoimmune Lymphoproliferative Syndrome

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT06730126

Phase 2

A Multicenter, Open-Label, Phase 2 Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Patients With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy

The purpose of this study is to evaluate the safety and pharmacokinetics of eflapegrastim in pediatric participants with solid tumors or lymphoma and treated w…

Solid TumorsLymphoma

Estimated

~$10 – $8,750

Spectrum Pharmaceuticals, IncNCT04570423

Observational

High-Resolution Assessment of California Table Grape Consumption on the Human Gut Microbiome-Immune Axis

This is a bio-specimen analysis and dietary intervention study that will examine whether the daily consumption of California table grape powder significantly m…

Gut Microbiomes

Estimated

~$10 – $6,250

Icahn School of Medicine at Mount SinaiNCT07797803

Observational

A Prospective, Multicenter, Single-arm, Post Market Study to Evaluate the Safety and Performance of the Signia™ Circular Stapler With Tri-Staple™ Technology in Elective Open or Minimally Invasive Left-sided Colon, Sigmoid, and Rectal Resections (SECURE)

The purpose of this study is to evaluate the safety and performance of the Signia™ power handle, Signia™ circular adapter, and Signia™ Tri-Staple™ 2.0 circular…

Colorectal AnastomosisLeft-sided Colon ResectionAnastomotic Leak+8 more

Estimated

~$10 – $7,500

Medtronic - MITGNCT07351071

Studies of the Natural History, Pathogenesis and Outcome of Ocular Disorders

Background: The National Eye Institute (NEI) wants to evaluate and provide standard treatment to people with eye diseases. Objective: To examine and treat p…

Eye Disease

Estimated

~$10 – $675

National Eye Institute (NEI)NCT02821767

Phase 2

A Phase 2 Open-label Multicenter Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inebilizumab in Children From 2 Years to Less Than 18 Years of Age With Generalized Myasthenia Gravis (gMG)

The primary objectives of this study are to characterize the pharmacokinetics (PK) and pharmacodynamics (PD) of inebilizumab administered in pediatric particip…

Generalized Myasthenia Gravis

Estimated

~$10 – $7,500

AmgenNCT06987539

A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression

Eosinophils are a type of white blood cell. Elevated eosinophil levels can damage the heart, nerves, and other organs, in the syndrome known as hypereosinophil…

EosinophiliaHypereosinophilic Syndrome

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT00091871

Biofluid Research on Age-Related or Inherited Neurodegeneration (BRAIN)

The aim of this study is to contribute to and continue to sustain a repository of blood samples, nucleic acid (DNA and/or RNA) samples, family history informat…

Frontotemporal Degeneration (FTD)ALS (Amyotrophic Lateral Sclerosis)Primary Progressive Aphasia (PPA)+12 more

Estimated

~$10 – $750

University of PennsylvaniaNCT07798700

Phase 4

PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr Adults (PREVENTABLE)

PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or p…

Cognitive Impairment, MildDementiaCardiovascular Diseases

Estimated

~$10 – $6,250

Duke UniversityNCT04262206