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27,292 recruiting studies available now

University of North Carolina Pleural Fluid Registry

Research with biospecimens such as blood, tissue, or body fluids can help researchers understand how the human body works. Researchers can make new tests to fi…

Lung CancerLung InfectionBreast Cancer+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

UNC Lineberger Comprehensive Cancer CenterNCT05620329

Phase 1

A Pilot Trial of Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Sickle Cell Disease

A promising approach for the treatment of genetic diseases is called gene therapy. Gene therapy is a relatively new field of medicine that uses genetic materia…

Sickle Cell DiseaseSickle Cell Anemia (HbSS, or HbSβ-thalassemia0)

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Daniel BauerNCT07708350

Phase 1

A Phase 1/2a, Multi-center, Open-label Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of PBGENE-DMD in Participants With Duchenne Muscular Dystrophy (FUNCTION-DMD)

The purpose of this Phase 1/2a trial is to evaluate the safety, tolerability, and preliminary efficacy of PBGENE-DMD in patients with DMD harboring mutations a…

Duchenne Muscular Dystrophy With Mutations Amenable to PBGENE-DMD

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Precision BioSciences, Inc.NCT07429240

Phase 2

Improving Balance and Mobility After Traumatic Brain Injury: A Randomized Controlled Trial Evaluating High Intensity Step Training

This study will explore whether the types and intensity of the interventions being delivered will yield measurable cognitive benefits in addition to improved m…

Traumatic Brain Injury

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Craig HospitalNCT05702138

Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

Continuation of the CARRA Registry as described in the protocol will support data collection on patients with pediatric-onset rheumatic diseases. The CARRA Reg…

Rheumatic Joint Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

Duke UniversityNCT02418442

Studies of the Natural History of Sickle Cell Disease

This study is not a treatment protocol and no experimental treatments are involved. Study participants may be seen as needed for clinical, translational and ba…

Pain Crisis

Estimated

~$10 – $675

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT00081523

Phase 2

A Phase 2 Study of Glofitamab as Monotherapy or in Combination With Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab in Richter's Transformation

This research is being done to evaluate Glofitamab by itself or in combination with Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab as possible treatments …

Chronic Lymphocytic LeukemiaRichter's Transformation

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Christine RyanNCT06043674

Phase 1

HERTHENA-Breast-01: A Phase 1b/2, Multicenter, Open-label, Dose-Finding Study to Evaluate the Safety and Antitumor Activity of Patritumab Deruxtecan in Participants With HER2 Positive Unresectable Locally Advanced Breast Cancer or Metastatic Breast Cancer

Researchers want to learn if patritumab deruxtecan (MK-1022) can treat certain breast cancers. The breast cancers being studied are HER2 positive unresectable …

Breast NeoplasmsBreast Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT06686394

Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

Bladder cancer is the most common urinary tract cancer and the 6th most common cancer in the US. Yet bladder cancer research is underfunded relative to other c…

Bladder CancerRecurrent Bladder CancerNon-muscle Invasive Bladder Cancer (NMIBC)

Estimated

~$10 – $750

Actual pay is set by the research site.

University of WashingtonNCT07225127

Phase 3

A Phase III, Open-label, Multicentre, Randomised Study Comparing Consolidation Treatment With AZD0120, an Autologous Dual Targeting Chimeric Antigen Receptor T-cell (CAR-T) Therapy Directed Against BCMA and CD19, Versus Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible (TE NDMM) (DURGA-6)

The purpose of this study is to measure the efficacy of AZD0120 compared with ASCT in terms of progression-free survival (PFS) according to the International M…

Newly Diagnosed Multiple Myeloma (NDMM)

Estimated

~$50 – $2,250

Actual pay is set by the research site.

AstraZenecaNCT07735637

Phase 2

Pilot Phase II Trial Evaluating Safety and Feasibility of Neoadjuvant Botensilimab and Balstilimab in Clear Cell Renal Cell Carcinoma (NEO RoBOT)

This phase II trial tests the effect of botensilimab and balstilimab before surgery (neoadjuvant) in treating patients with high-risk clear cell renal cell can…

Clear Cell Renal Cell CarcinomaStage II Renal Cell Cancer AJCC v8Stage III Renal Cell Cancer AJCC v8+1 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT07516366

Observational

A Randomized Controlled Study of the Prevail Drug-Coated Balloon in Subjects With In-stent Restenosis and a Single Arm Prospectively Enrolled Study of the Prevail Drug-Coated Balloon for de Novo Lesions in Small Vessel Disease (Prevail Global).

The purpose of the study is to evaluate the clinical safety and efficacy of the Prevail DCB.

Coronary Artery Disease

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Medtronic VascularNCT06535854