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27,293 recruiting studies available now

A Phase 2, Open-label Study of VS-7375, an Oral KRAS G12D (ON/OFF) Inhibitor, as Monotherapy and With Cetuximab, in Patients With Metastatic KRAS G12D-Mutated Pancreatic Cancer (TARGET-D 201)

This study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab in patients with metastatic KRAS G12D - mutated Pancreatic Ca…

Pancreatic Ductal Adenocarcinoma (PDAC)G12D Mutated KRAS

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Verastem, Inc.NCT07644559

Identification Of Lung Cancer In Never-Smoking Individuals Using A Non-Invasive Volatile Organic Compound (VOCs) Biological Platform With Urine Specimens

The goal of this observational study is to learn whether a urine-based test that measures volatile organic compounds (VOCs) can help detect lung cancer in peop…

Lung Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

Thomas Jefferson UniversityNCT07871656

Observational

Support Towards Addiction Recovery for Individuals With Criminal Legal System Involvement: The STAR Project

The goal of this clinical trial is to determine whether a new, paired coaching intervention improves outcomes for individuals with criminal legal system involv…

Addiction

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Martha TillsonNCT07596251

Phase 2

Allogeneic Stem Cell Transplantation for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion - NYMC 588

Children, adolescents, and young adults with malignant and non-malignant conditionsundergoing an allogeneic stem cell transplantation (AlloSCT) will have the s…

Acute LeukemiaSevere Aplastic AnemiaNon-hodgkin Lymphoma+6 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Mitchell CairoNCT04099966

Gonadal Tissue Freezing for Fertility Preservation in Individuals at Risk for Ovarian Dysfunction, Premature Ovarian Insufficiency and Clinically Indicated Gonadectomy

Background: Turner Syndrome, galactosemia, and premature ovarian insufficiency are all conditions that may make it very hard or impossible for a person to bec…

Turner SyndromePost-menarcheal AdolescentsOvarian Disfunction+3 more

Estimated

~$10 – $675

Actual pay is set by the research site.

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NCT04948658

Phase 2

An Open-Label Phase 2 Study of N-Acetyl-D-Mannosamine (ManNAc) in Subjects With Podocyte Diseases

Background: Podocyte diseases are a group of kidney conditions that include focal segmental glomerulosclerosis (FSGS), minimal change disease (MCD), and membr…

Focal Segmental GlomerulosclerosisMinimal Change DiseaseMembranous Nephropathy

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Human Genome Research Institute (NHGRI)NCT06664814

An International Observational Registry Study to Further Describe Long-term Safety and Effectiveness of Palovarotene in Patients With Fibrodysplasia Ossificans Progressiva (FOP)

The participants in this registry study will have fibrodysplasia ossificans progressiva (FOP). FOP is an ultra-rare, severely disabling disease characterized …

Fibrodysplasia Ossificans Progressiva

Estimated

~$10 – $1,125

Actual pay is set by the research site.

IpsenNCT06089616

Phase 2

A Double-Blind, Placebo-Controlled, Multicenter, Randomized Phase 2 Trial Evaluating the Efficacy and Safety of Felzartamab in Recipients of Kidney Transplants With Late Isolated Microvascular Inflammation (MVI)

In this study, researchers will learn more about a drug called felzartamab in people who have received a kidney transplant and later developed a condition call…

Microvascular Inflammation

Estimated

~$75 – $3,000

Actual pay is set by the research site.

BiogenNCT07219043

Observational

Adjunctive Motivational Alcohol Intervention to Prevent Intimate Partner Violence

This is a study to provide much-needed experimental data on the efficacy of a brief alcohol Motivational Enhancement Therapy (MET) pre-group intervention for V…

Alcohol Use and Intimate Partner Violence

Estimated

~$10 – $675

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT05287711

Phase 3

A Phase 3, Multi-Center Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Risankizumab With Open-Label Induction, Randomized Double-Blind Maintenance, and Open-Label Long-Term Extension Periods in Pediatric Subjects (2 to < 18 Years of Age) With Moderately to Severely Active Ulcerative Colitis

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine)…

Ulcerative Colitis

Estimated

~$50 – $2,250

Actual pay is set by the research site.

AbbVieNCT07071519

Phase 2

An Open-label Extension Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of ORKA-001 in Participants With Moderate-to-Severe Plaque Psoriasis

An open-label extension (OLE) study to evaluate the long-term safety and efficacy of ORKA-001 in adult participants with moderate-to-severe plaque psoriasis, w…

Plaque Psoriasis

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Oruka Therapeutics, Inc.NCT07449702

Phase 2

A Phase 2, Parallel-Group, Double-Blind Study to Investigate Weight Management With LY4086940 Compared With Placebo in Adult Participants With Obesity or Overweight and Without Type 2 Diabetes

The purpose of this study, performed under the master protocol W8M-MC- CWMM (NCT06143956), is to evaluate the efficacy and safety of LY4086940 compared with pl…

ObesityOverweight

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Eli Lilly and CompanyNCT07890376