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Long-term Oncologic Safety of Nipple Sparing Mastectomy in Women With High Penetrance Germline Pathogenic Variants in Breast Cancer Susceptibility Genes

Patients with a germline pathogenic variant (GPV) in high-penetrance breast cancer susceptibility genes who are considering risk reducing mastectomy (RRM) ofte…

Breast Cancer Surgery

Estimated

~$10 – $750

Actual pay is set by the research site.

Sir Mortimer B. Davis - Jewish General HospitalNCT06888388

Observational

Sensor Ankle Brace for Special Operations Rehabilitation - Phase 2

The primary purpose of this study overall is to validate a modified version of a commercially available ankle brace. Inertial measurement unit sensors will be …

GaitBalanceBiomechanical Data+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Indiana UniversityNCT07776223

A Prospective Longitudinal Outcomes Registry of Complex Regional Pain Syndrome Type 1 (CRPS-1) in Participants Treated With Neridronate in the CRPS-RISE Trial and/or Open-Label Extension (OLE)

The goal of this observational study is to learn about how well neridronate keeps working in the months after treatment. For 12 or up to 24 months while the re…

Complex Regional Pain Syndrome I (CRPS I)

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Ambros Therapeutics, Inc.NCT07811362

Phase 1

A Phase I/II Study Evaluating the Preliminary Safety and Efficacy of Treprostinil (Remodulin®) In Reducing Ischemia-Reperfusion Injury During De Novo Adult Kidney Transplantation

The objectives of this study are to test the preliminary safety and efficacy of a two-day peri-operative course of treprostinil in reducing ischemia-reperfusio…

Ischemia Reperfusion InjuryDelayed Graft Function

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Rhode Island HospitalNCT04005469

Intermuscular Coherence: A Biomarker for Early Diagnosis and Follow-up of ALS

The specific aims of this study are to: 1. Determine if a painless and quick measurement of muscle activity using surface electrodes can help with the diagnos…

Amyotrophic Lateral Sclerosis

Estimated

~$10 – $750

Actual pay is set by the research site.

University of ChicagoNCT05104710

Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers

Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous disease that affects only a fraction of those who smoke tobacco. The origin of this variability…

CopdSmokingTobacco Use

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT04722835

SPIROMICS Study of Early COPD Progression (SOURCE)

This is an observational study of 1000 participants to further define the nature of early chronic obstructive pulmonary disease (COPD) in younger, at-risk indi…

COPD, Early-Onset

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Massachusetts, WorcesterNCT05033990

Phase 3

A Phase III, Multicenter, Open-Label Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Emicizumab Prophylaxis in Patients With Type 3 Von Willebrand Disease

This is a Phase III, multicenter, open-label clinical study designed to evaluate the efficacy, safety, pharmacokinetics, and pharmacodynamics of emicizumab pro…

Von Willebrand Disease, Type 3

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Hoffmann-La RocheNCT06998524

Phase 2

Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Triple Negative Breast Cancer

This is a prospective radiation dose-finding, phase 2 expansion study of the Triple Negative (TN) cohort of the multicenter randomized study P-RAD (A Randomize…

Breast CancerTriple Negative Breast Cancer (TNBC)HER2-Negative Breast Carcinoma+1 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

UNC Lineberger Comprehensive Cancer CenterNCT07276880

Observational

Randomized Controlled Trial Comparing Clinical Outcomes of Patients Treated Surgically With Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries

This project consists of a randomized controlled study design. Study candidates will include all patients 18 years or older, who were evaluated at UCSD and fou…

Ankle InjuriesSyndesmotic InjuriesAnkle Fractures

Estimated

~$10 – $750

Actual pay is set by the research site.

University of California, San DiegoNCT05729542

Phase 1

A Combined Single and Multiple Ascending Dose Phase 1a/1b, Double-blind, Placebo-Controlled, and Food-effect Study to Evaluate the Safety and Pharmacokinetics of Oral KM-023 in Healthy Participants. Followed by a 3-month Open Label Study to Evaluate the Safety, Pharmacokinetics and Efficacy of Oral KM-023 in Olmsted Syndrome Patients

The trial is conducted in order to assess the safety of KM-023 and to observe what effects, both beneficial and adverse, it has on the body, and the way the bo…

Olmsted Syndrome

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Orvida Pharma (formerly Kamari Pharma)NCT07090889

A Sub-registry to Observe the Effect of Alglucosidase Alfa or Avalglucosidase Alfa Treatment on Pregnancy and Infant Growth in Women With Pompe Disease

This Sub-registry is a multicenter, international, longitudinal, observational, and voluntary program designed to track pregnancy outcomes for any pregnant wom…

Glycogen Storage Disease Type II (GSD-II)Pompe Disease (Late-onset)Glycogenesis 2 Acid Maltase Deficiency

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Genzyme, a Sanofi CompanyNCT00567073